Aztreonam-avibactam is under clinical development for multidrug-resistant Gram-negative infections. We evaluated activity against 341 recent clinical isolates. The addition of avibactam to aztreonam had no effect on the anaerobic activity of aztreonam. This work shows that aztreonam-avibactam lacks activity against anaerobic organisms.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672875 | PMC |
| http://dx.doi.org/10.1128/Spectrum.01908-21 | DOI Listing |
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