AI Article Synopsis
- This review investigates the effects of polyunsaturated fatty acid (PUFA) supplementation on reproductive outcomes for women using assisted reproductive technology (ART).
- A systematic search identified 4 randomized control trials published from January 1978 to 2021, focusing on primary outcomes like pregnancy and live birth rates, as well as secondary measures such as implantation and fertilization rates.
- The findings highlight a scarcity of high-quality research, indicating the need for more robust studies before PUFAs can be clinically recommended for women undergoing ART.
Article Abstract
This review explores the impact of polyunsaturated fatty acid (PUFA) supplementation in women undergoing assisted reproductive technology (ART) on reproductive outcomes. A systematic search of English peer-reviewed journals was carried out using MEDLINE, EMBASE, and the Cochrane Library to identify articles published from January 1978 to 2021. The primary outcomes assessed included pregnancy and live birth rates. Secondary outcome measures included: (i) implantation rate; (ii) fertilisation rate; (iii) number of oocytes retrieved; (iv) number of metaphase II (MII) oocytes; (v) blastocyst conversion; and (vi) embryo quality. A total of 4 randomised control trials (RCTs) met the inclusion criteria. There is a lack of high-quality research to support widespread dietary supplementation with PUFAs in women undergoing ART. Prior to its clinical recommendation, there is a need for well-designed RCTs to facilitate an in-depth understanding of PUFA supplementation in women undergoing ART.
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| http://dx.doi.org/10.1080/14647273.2021.2007421 | DOI Listing |
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