Impact of Comorbid Personality Disorders on Depression Treatment in Routine Outpatient Care.

Am J Psychother

Department of Clinical Psychological Science, Maastricht University, ​Maastrich, the Netherlands (van Bronswijk, van Dijk, Peeters); Department of Psychiatry and Psychology, Maastricht University Medical Center+, Maastricht, the Netherlands (van Bronswijk); Department of Mood Disorders, PsyQ Haaglanden, the Hague, the Netherlands (van Dijk, van den Boogaard); Parnassia Psychiatric Institute, the Hague (Deen); Institute of Psychology, Leiden University, Leiden, the Netherlands (Deen); Department of Psychiatry, Radboud University Medical Center, Nijmegen, the Netherlands (Ruhé); Donders Institute for Brain, Cognition and Behavior, Radboud University, Nijmegen (Ruhé); Pro Persona Mental Healthcare, and Behavourial Science Institute, Radboud University, Nijmegen (Spijker).

Published: December 2021

Objective: The impact of personality disorder on treatment effectiveness for depression has been debated, and study results have been inconsistent. However, studies that report a negative impact of personality disorders on depression treatment outcomes are often characterized by uncontrolled treatment designs. Within such contexts, individuals with depression and personality disorders are at risk to receive suboptimal treatment. The aim of this retrospective observational study was to investigate whether and to what extent comorbid personality disorders were associated with the type and amount of depression treatment received in routine outpatient care.

Methods: Retrospectively extracted data from electronic records of 1,455 outpatients treated for depression at several sites of a nationwide mental health provider in the Netherlands were included. The type and number of treatment sessions and visits were analyzed by using regression models.

Results: Individuals with depression and comorbid personality disorders received more psychotherapy sessions than individuals without personality disorders, irrespective of depression severity. The number of pharmacotherapy sessions and supportive and crisis visits did not differ between individuals with and without comorbid personality disorders.

Conclusions: Individuals with depression and personality disorders received more intensive treatment than individuals without comorbid personality disorders. These results conflict with treatment guidelines and recommendations from high-quality studies and may be indicative of overtreatment among this large group of patients.

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http://dx.doi.org/10.1176/appi.psychotherapy.202120200046DOI Listing

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