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Robust air-stable cyclometalated π-allyliridium ,-benzoates modified by ()-tol-BINAP catalyze the reaction of secondary aliphatic amines with racemic alkyl-substituted allylic acetates to furnish products of allylic amination with high levels of enantioselectivity. Complete branched regioselectivities were observed despite the formation of more highly substituted C-N bonds.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764998 | PMC |
| http://dx.doi.org/10.1021/acs.orglett.1c04135 | DOI Listing |
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