The basic reproduction ratio R of more general periodic and time-delayed impulsive model which the period of model coefficients is different from that of fixed impulsive moments, is developed. That R is the threshold parameter for the stability of the zero solution of the associated linear system is also shown. The developed theory is further applied to a swine parasitic disease model with pulse therapy. Threshold results on its global dynamics in terms of R are obtained. Some numerical simulation results are also given to support our main results.

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http://dx.doi.org/10.3934/mbe.2022038DOI Listing

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