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http://dx.doi.org/10.1016/j.adro.2021.100787 | DOI Listing |
Cureus
October 2024
Radiation Oncology, Max Super Speciality Hospital, Ghaziabad, IND.
The preferred treatment for medically inoperable early-stage endometrial cancer (EC) is definitive radiation therapy (RT), either in the form of brachytherapy (BT) alone or in combination with external beam radiotherapy (EBRT). This case report details a modified brachytherapy approach for a 59-year-old female patient who was known to have multiple comorbidities, poor performance status, and progressive slowness in activities of daily living. She presented with a complaint of post-menopausal bleeding per vaginum, for which she underwent investigations and was diagnosed with a case of endometrial adenocarcinoma, International Federation of Gynecology and Obstetrics (FIGO) stage IA and grade I.
View Article and Find Full Text PDFJ Environ Manage
November 2024
Department of Civil Engineering, Institute of Infrastructure, Technology, Research and Management, Ahmedabad, 380026, India. Electronic address:
The dredged soil obtained from maintenance activities of water bodies has emerged as a potential alternate fill material for infrastructure development. However, dredged soil requires stabilization due to high initial water content, low shear strength and high compressibility. Among several methods, stabilization of dredged soil by using electrokinetics is one of the effective ground improvement techniques that uses electric field to dewater and strengthen the soil.
View Article and Find Full Text PDFLymphopenia in coronavirus disease (COVID-19) is associated with increased mortality. To explore the association between lymphopenia, host response aberrations, and mortality in patients with lymphopenic COVID-19. We determined 43 plasma biomarkers reflective of four pathophysiological domains: endothelial cell and coagulation activation, inflammation and organ damage, cytokine release, and chemokine release.
View Article and Find Full Text PDFClin Pharmacol Ther
October 2023
Department of Hospital Pharmacy and Clinical Pharmacology, Amsterdam UMC, Amsterdam, The Netherlands.
Methotrexate polyglutamates (MTX-PG) concentrations in red blood cells (RBCs) have been suggested as a biomarker of response in patients with rheumatoid arthritis (RA) receiving low-dose MTX therapy. We investigated the association and interpatient variability between RBC-MTX-PG -exposure and response in patients with RA starting MTX. Data of three prospective cohorts were available.
View Article and Find Full Text PDFExpert Rev Clin Pharmacol
June 2023
Department of Clinical Pharmacology Sciences, Gilead Sciences, Foster City.
Introduction: Bladder cancer (BC) is the sixth most common type of cancer with epithelial/urothelial and non-urothelial origins. Urothelial carcinoma (UC) involves neoplastic cells of epithelial origin and accounts for 90% of all BC cases. Current review aims to discuss the latest advances and challenges in the treatment of UC with an emphasis on clinical pharmacology considerations.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!