Anthraquinones with potential antiproliferative activities from the fruits of .

Nat Prod Res

Key Laboratory of Tropical Medicinal Resources Chemistry of Ministry of Education, Hainan Normal University, Haikou, P.R. China.

Published: May 2023

The phytochemical investigation on the fruits of led to the isolation and characterization of a new anthraquinone, moricitrifone (), along with seven known anthraquinones (-). The chemical structure of was elucidated by extensive spectral analyses. The known compounds (-) were identified by comparing their spectral data with those reported in the literature. The antiproliferative activities of all isolated anthraquinones (-) against five human cancer cell lines: HL-60, SMMC-7721, A-549, MCF-7 and SW480 were evaluated . Compounds - exhibited remarkable antiproliferative activities with IC values ranging from 0.26 ± 0.05 to 16.58 ± 0.18 μM, which were comparable to those of doxorubicin.

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Source
http://dx.doi.org/10.1080/14786419.2021.2012670DOI Listing

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