Composite materials are effective adsorbents for the removal of various types of contaminants, such as pharmaceutical products. However, they require improvement to achieve a good adsorption capacity. This study presents the development of a promising adsorbent: silica/chitosan modified with different proportions of glutaraldehyde, which involves the D-glucosamine units from chitosan. The developed materials were evaluated for their ability to remove diclofenac sodium. The adsorption data showed that the diclofenac adsorption efficiency increased with increasing degree of glutaraldehyde crosslinking. The equilibrium and kinetic data were well fit by the Liu and Elovich models, respectively, and the maximum adsorption capacity was 237.8 mg/g. Therefore, it can be assumed that the process is predominantly chemical and exothermic, with a high affinity between the adsorbents and diclofenac sodium. The adsorption mechanisms were investigated to better understand the interactions, and the predominance of covalent bonds with the self-polymerized glutaraldehyde was verified.
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