Stroke is a leading cause of disability in the U.S. Hand impairment is a common consequence of stroke, potentially impacting all facets of life as the hands are the primary means of interacting with the world. Typically, therapy is the prescribed treatment after stroke. However, a majority of stroke survivors have limited recovery and thus chronic impairment. Assistive, rather than therapeutic, devices may help these individuals restore lost function and improve independence and engagement in society. Current assistive devices, however, typically fail to address the greatest barriers to successful use with stroke survivors. In the hand, weakness and incoordination arise from a seemingly paradoxical combination of limited voluntary activation of muscles and involuntary neuromuscular hyperexcitability. Thus, profound strength deficits can be accompanied by substantial forces opposing the intended movement. The assistive device presented in this paper can provide both sufficient flexion and extension assistance to overcome these barriers. A single actuator for each digit provides flexion or extension assistance through push-pull cables guided along the dorsal side of the hand. User intent can be decoded from Electromyographic (EMG) signals to drive the device throughout the movement. EMG control is customized to the capabilities of each user by examining the voluntary EMG workspace.
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http://dx.doi.org/10.1109/EMBC46164.2021.9629805 | DOI Listing |
Since treatment with anticoagulants can prevent recurrent strokes, identification of patients at risk for incident AF after stroke is crucial. We aimed to investigate whether the addition of AF polygenic risk scores (PRS) to existing clinical risk predictors could improve prediction of AF after stroke. Patients diagnosed with ischemic stroke at Massachusetts General Hospital between 2003-2017 were included.
View Article and Find Full Text PDFJ Clin Neurosci
January 2025
Department of Educational Management, Pattimura University, Ambon, Indonesia.
BMJ Open
January 2025
Department of Health Sciences, Brunel University of London, Uxbridge, UK
Objective: To investigate the safety, feasibility and acceptability of the Neurofenix platform for upper-limb rehabilitation in acute and subacute stroke.
Design: A feasibility randomised controlled trial with a parallel process evaluation.
Setting: Acute Stroke Unit and participants' homes (London, UK).
PLoS One
January 2025
Faculty of Health and Medicine, Lancaster University, Lancaster, United Kingdom.
Background: Strokes are becoming more common, and with improving survival rates, the prevalence of stroke survivors has increased. Almost half of chronic stroke survivors are cognitively impaired, and healthcare services are struggling to manage these patients, leaving some feeling "abandoned". Several systematic reviews have investigated the effect of physical exercise and cognition-orientated interventions on post-stroke cognitive impairment, and have produced conflicting findings, making it difficult for clinicians and guideline producers to make evidence-based decisions.
View Article and Find Full Text PDFDisabil Rehabil
January 2025
Department of Rehabilitation Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
Purpose: To explore associations of environmental and personal factors, participation, and health-related quality of life (HR-QoL) with physical behavior (PB) after subarachnoid hemorrhage (SAH).
Materials And Methods: PB, expressed in duration and distribution of physical activity (PA; walking, running, cycling) and sedentary behavior (SB; lying/sitting) and PA intensity was assessed with the Activ8 accelerometer during 7 days. Environmental and personal factors (social influence, health-condition, illness-perception, self-efficacy, fatigue, mood, kinesiophobia, cognition, coping, sleep), participation and HR-QoL, were assessed with validated questionnaires.
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