Evaluation of Amorphous Silicon Carbide on Utah Electrode Arrays by Thermal Accelerated Aging.

Long-term microelectrode arrays (MEAs) are essential devices for studying neural activity and stimulating neurons for treating neurological disorders or for recording neural activity to control prosthesis. However, practical use of MEAs is impeded by unreliable chronic stability inside the host body. We are proposing to implement amorphous silicon carbide (a-SiC) as a replacement for the current standard practice of using Parylene-C encapsulation on commercial Utah electrode arrays (UEAs) manufactured by Blackrock Neurotech. By using thermal accelerated aging (TAA), we can theoretically evaluate the lifetime stabilities in comparatively short time. After 255 days at 87°C in phosphate-buffered saline (PBS), a device has theoretically reached ~22 years at 37°C in PBS. We report on a study of an a-SiC UEA using stability criteria of impedance (Z < 70 kΩ) and cathodal charge storage capacity (CSC > 10 mC/cm). At 255 days, no total electrode failures have been observed.Clinical Relevance- This research demonstrates the suitability of a-SiC to encapsulate MEAs during under long-term stability in saline environments.