Cardiovascular diseases (CVD) have been identified as one of the most common causes of death in the world. Advanced development of imaging techniques is allowing timely detection of CVD and helping physicians in providing correct treatment plans in saving lives. Segmentation and Identification of various substructures of the heart are very important in modeling a digital twin of the patient-specific heart. Manual delineation of various substructures of the heart is tedious and time-consuming. Here we have implemented Dense VNet for detecting substructures of the heart from both CT and MRI multimodality data. Due to the limited availability of data we have implemented an on-the-fly elastic deformation data augmentation technique. The result of the proposed has been shown to outperform other methods reported in the literature on both CT and MRI datasets.
Background: STereotactic Arrhythmia Radioablation (STAR) is a novel noninvasive method for treating arrythmias in which external beam radiation is directed towards subregions of the heart. Challenges for accurate STAR targeting include small target volumes and relatively large patient motion, which can lead to radiation related patient toxicities. 4D Cone-beam CT (CBCT) images are used for stereotactic lung treatments to account for respiration-related patient motion.
Introduction: While there is a growing amount of data on the cardiac toxicity of radiotherapy (RT) in relation to its impact on cardiac sub-structures (CSS), there are only few studies addressing this issue in patients followed for esophageal cancer (ESOC). We aimed to evaluate the association between independent parameters of dose received by CSS and major cardiac events (MACEs) in this population.
Materials And Methods: We retrospectively analyzed 122 patients treated with exclusive RT or chemo-RT for ESOC.
Since 1968, the United States Transuranium and Uranium Registries (USTUR) has studied the biokinetics and tissue dosimetry of uranium and transuranium elements in nuclear workers. As part of the USTUR collaboration with the Million Person Study (MPS) of Low-Dose Health Effects, radiation dose to different parts of the human heart is being estimated for workers with documented intakes of 239Pu or 226Ra. The study may be expanded for workers with intakes of 238U and other radionuclides.
Purpose: The association of cardiac dosimetric parameters with survival in lung cancer patients is well established. However, most research has concentrated on patients undergoing definitive treatment. This study aims to investigate the relationship between cardiac dosimetric parameters and survival in patients receiving postoperative radiotherapy (PORT).
This review article aims to synthesize existing data on radiation-induced heart diseases in patients undergoing chest radiation therapy and also explores cardiac-sparing techniques to mitigate cardiotoxic effects. We conducted a comprehensive database search to review and consolidate data regarding chest radiotherapy and effects on the heart as well as techniques to minimize exposure to the heart. The research findings demonstrate associations between radiation exposure to cardiac substructures and subsequent cardiotoxicity.
