Estrogens and phytoestrogens in body functions.

Neurosci Biobehav Rev

Department Medicine, Surgery and Neuroscience, University of Siena, Siena, Italy. Electronic address:

Published: January 2022

Estrogens are the hormones of reproduction in women as well as of many other important functions in the male and female body. They undergo significant changes in the different phases of life, e.g. during puberty, pregnancy or at menopause/andropause. Phytoestrogens are natural non-steroidal phenolic plant compounds that can mimic the activity of estrogens and their beneficial effects in women and in men. This narrative review summarizes the literature on the physiological role of estrogens and the several potential health benefits of phytoestrogens, with particular attention given to the possible role of phytoestrogens in aging.

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http://dx.doi.org/10.1016/j.neubiorev.2021.12.007DOI Listing

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