AI Article Synopsis
- - Actinic prurigo is a rare skin condition that causes itching and is triggered by sunlight exposure.
- - A case study reports an 11-year-old girl with this condition significantly improved after using Polypodium leucotomos extract, with no adverse effects observed.
- - Polypodium leucotomos has properties that help modulate the immune response and reduce inflammation, which helps protect the skin from UV damage associated with photodermatoses.
Article Abstract
Actinic prurigo is a rare pruritic photodermatosis. We report the use of Polypodium leucotomos extract in an 11-year-old female patient with actinic prurigo, resulting in a significant attenuation of her disease without development of adverse effects to date. Polypodium leucotomos exerts a pleiotropic immunomodulatory and antioxidant effect by shifting the balance from pro- to an antiinflammatory cytokine environment. This counteracts the effects of UV-induced cellular damage characteristic of photodermatoses.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/pde.14876 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Exploring adult-onset actinic prurigo in Thailand.
Dermatol Reports
September 2024
Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Article Synopsis
- Actinic prurigo (AP)
- is a rare skin condition primarily affecting adults in Thailand, with a mean onset age of 45.5 years, and is more common in males (66.7%) compared to females.
- Clinical features
- include papules mostly on the face and upper extremities, with some patients experiencing mucositis; phototesting showed varying sensitivity to UVA and UVB light.
- Treatment outcomes
- indicate that 60% of patients received systemic immunosuppressants; while the median time for clinical improvement was about 8.6 months, only a small number achieved complete remission.
Treatment of actinic prurigo with dupilumab in an adolescent.
Int J Dermatol
January 2025
Department of Dermatology, Mayo Clinic, Rochester, MN, USA.
Successful treatment of refractory late-onset actinic prurigo with tofacitinib.
Int J Dermatol
December 2024
Department of Dermatology, Venereology and Leprosy, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital, New Delhi, India.
Successful treatment of actinic prurigo with baricitinib in an 8-year-old child: A case report.
Pediatr Dermatol
November 2024
Department of Dermatology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Article Synopsis
- - Actinic prurigo is a rare skin condition that causes itchy, raised lesions and is particularly difficult to treat, especially in children.
- - Effective management requires strict sun protection, as symptoms can last for most of the year.
- - A case study of an 8-year-old patient showed quick improvement of symptoms using baricitinib, a medication not commonly used for this condition.
Complete response of actinic prurigo to oral baricitinib.
J Dtsch Dermatol Ges
June 2024
Dermatology Department, Hospital Clínic de Barcelona, Universitat de Barcelona, Barcelona, Spain.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!