[Progress of IgG4 related sino-nasal diseases].

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi

Published: November 2021

IgG4 related disease(IgG4-RD)is a newly recognized chronic fibroinflammatory disease in recent years.It is often accompanied by the significant elevation of serum IgG4 level,but the diagnostic specificity of the elevation is not high.The diagnosis is mainly based on histopathology,which is characterized by dense IgG4 positive plasma cell infiltration,storiform fibrosis and obliteran phlebitis.IgG4-RDcan involve various organs of the body,but less involve the nasal cavity and paranasal sinuses.The nasal symptoms of IgG4-RD are lack of specificity,so it is easier to be missed and misdiagnosed.PET/CT has important value in the diagnosis and differential diagnosis of the disease.We reviewed the relevant studies of IgG4-RD in nasal cavity and paranasal sinus in recent years,in order to improve the understanding of IgG4-RD in nasal cavity and paranasal sinuses and to improve the diagnosis and treatment rate.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10128376PMC
http://dx.doi.org/10.13201/j.issn.2096-7993.2021.11.018DOI Listing

Publication Analysis

Top Keywords

nasal cavity
12
cavity paranasal
12
igg4-rd nasal
8
[progress igg4
4
igg4 sino-nasal
4
sino-nasal diseases]
4
diseases] igg4
4
igg4 disease(igg4-rd)is
4
disease(igg4-rd)is newly
4
newly recognized
4

Similar Publications

Background And Objectives: The Chordate System administers kinetic oscillation stimulation (K.O.S) into the nasal cavity thereby potentially modulating the activity of trigemino-autonomic reflex.

View Article and Find Full Text PDF

Loss of facial features can result from a variety of traumatic events. Throughout history, humans have worked to develop materials and methods to repair such defects. Epithesis first appeared in medical literature in the 16th century.

View Article and Find Full Text PDF

Background: Abnormal protein depositions of amyloid β and tau are present in the nasal cavity in patients with Alzheimer's disease. This finding raises an idea that nasal tissues would be a promising source of diagnostic biomarkers for Alzheimer's disease. However, the amounts of amyloid β and tau are extremely small, making it difficult to quantify the levels using conventional methods such as ELISA, and thus it is challenging to utilize them for the diagnostic biomarkers.

View Article and Find Full Text PDF

Background: Insulin resistance (IR) is associated with abnormal tau-phosphorylation and IR markers in AD brain co-localize with neurofibrillary tangles. One strategy to overcome brain IR is to increase brain insulin is via intranasal insulin (INI) administration using specialized intranasal devices that deliver insulin to the brain. Our recent INI vs.

View Article and Find Full Text PDF

Background: Insulin resistance (IR) is associated with abnormal tau-phosphorylation and IR markers in AD brain co-localize with neurofibrillary tangles. One strategy to overcome brain IR is to increase brain insulin is via intranasal insulin (INI) administration using specialized intranasal devices that deliver insulin to the brain. Our recent INI vs.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!