Traffic accidents have significant financial and social impacts. Reducing the losses caused by traffic accidents has always been one of the most important issues. This paper presents an effort to investigate the factors affecting the accident severity of drivers with different driving experience. Special focus was placed on the combined effect of driving experience and age. Based on our dataset (traffic accidents that occurred between 2005 and 2021 in Shaanxi, China), CatBoost model was applied to deal with categorical feature, and SHAP (Shapley Additive exPlanations) model was used to interpret the output. Results show that accident cause, age, visibility, light condition, season, road alignment, and terrain are the key factors affecting accident severity for both novice and experienced drivers. Age has the opposite impact on fatal accident for novice and experienced drivers. Novice drivers younger than 30 or older than 55 are prone to suffer fatal accident, but for experienced drivers, the risk of fatal accident decreases when they are young and increases when they are old. These findings fill the research gap of the combined effect of driving experience and age on accident severity. Meanwhile, it can provide useful insights for practitioners to improve traffic safety for novice and experienced drivers.
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http://dx.doi.org/10.3390/ijerph182312725 | DOI Listing |
Front Public Health
December 2024
School of Public Health, Shandong Second Medical University, Weifang, China.
Background: Improving system coordination is a pivotal strategy and a critical pathway for social governance. Chinese society is currently facing a significant challenge in aligning the allocation of health resources with economic development. Evaluating the level of coordinated development within the system can provide valuable insights to support the construction of a more coordinated China and foster high-quality development.
View Article and Find Full Text PDFCancer Rep (Hoboken)
December 2024
Department of Hematology and Clinical Immunology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Background: Erdheim-Chester disease (ECD) is a rare form of non-Langerhans cell histiocytosis with diverse clinical manifestations, often associated with mutations in the mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) pathway. BRAF and KRAS mutations, which are driver mutations of oncogenes, participate in the same signaling pathway (MAPK/ERK pathway) and are usually mutually exclusive. We report a case of ECD with concurrent BRAF and KRAS mutations treated using BRAF and MEK inhibitors.
View Article and Find Full Text PDFOpen Forum Infect Dis
January 2025
Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan, USA.
Disparities in coronavirus disease 2019 mortality are driven by inequalities in group-specific incidence rates (IRs), case fatality rates (CFRs), and their interaction. For emerging infections, such as severe acute respiratory syndrome coronavirus 2, group-specific IRs and CFRs change on different time scales, and inequities in these measures may reflect different social and medical mechanisms. To be useful tools for public health surveillance and policy, analyses of changing mortality rate disparities must independently address changes in IRs and CFRs.
View Article and Find Full Text PDFBiodivers Data J
December 2024
Institute for Biodiversity and Environmental Research, Universiti Brunei Darussalam, Bandar Seri Begawan, Brunei Institute for Biodiversity and Environmental Research, Universiti Brunei Darussalam Bandar Seri Begawan Brunei.
Understanding how abiotic factors influence Bornean tropical tree communities and diversity is a key aspect in elucidating the mechanisms of species co-existence and habitat preferences in these biodiverse forests. We focused on investigating forest structure, tree diversity and community composition of lowland Bornean heath forests in Brunei Darussalam, within two 0.96 ha permanent forest plots at Bukit Sawat Forest Reserve and Badas Forest Reserve.
View Article and Find Full Text PDFFront Pediatr
December 2024
Laboratory of Translational Research, Children's Hospital of Brasília, Brasília, Brazil.
Introduction: There is consistent evidence that may be a driver gene in B-ALL and that selected cases may benefit from the use of FLT3 inhibitors. Our study was conducted to evaluate the frequency and types of FLT3 mutations in pediatric patients with B-ALL, the relative expression of this gene, and their influence on clinical evolution.
Methods: We evaluated 156 children with B-ALL treated between July 2018 and September 2023.
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