AI Article Synopsis
Article Abstract
Electronic circular dichroism (ECD) can be used to study various aspects of self-assembly (definition of stoichiometric ratios, chirality amplification during self-assembly, host-guest complexation). In this work, we show that ECD is a valuable tool for monitoring the self-assembly of chiral peptide-based capsules. By analyzing the signs, intensities, and temperature dependences of ECD bands, the effects of the non-specific processes can be separated from the restriction of intramolecular motion (RIM) caused by discrete self-assembly. Analysis of experimental and theoretical ECD spectra show that the differences between assembled and non-assembled species originate from induction of inherently chiral conformation and restriction of conformational freedom that leads to amplification of ECD signals during self-assembly of discrete species.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658961 | PMC |
| http://dx.doi.org/10.3390/molecules26237100 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Safe controller design for circular motion of a bicycle robot using control Lyapunov function and control barrier function.
ISA Trans
December 2024
School of Engineering Technology, Purdue University, West Lafayette, IN, USA. Electronic address:
This paper investigates the safety control problem of a bicycle robot with front-wheel drive and without a trail or mechanical regulator during circular motion. Constraints on the drive angular speed necessary for the bicycle to achieve circular motion are proposed. In practical robot systems, bounded input disturbances are inevitable.
View Article and Find Full Text PDFAmbient fine particulate matter provokes multiple modalities of cell death via perturbation of subcellular structures.
Environ Int
December 2024
Key Laboratory of Environmental Medicine Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing, Jiangsu 210009, China; Department of Toxicology, School of Public Health, Anhui Medical University, Hefei, Anhui 230032, China. Electronic address:
Fine particulate matter (PM2.5) is increasingly recognized for its detrimental effects on human health, with substantial evidence linking exposure to various forms of cell death and dysfunction across multiple organ systems. This review examines key cell death mechanisms triggered by PM2.
View Article and Find Full Text PDFDioxin-like polychlorinated biphenyls (dl-PCB) in hydrochars and biochars: Review of recent evidence, pollution levels, critical gaps, formation mechanisms and regulations.
J Hazard Mater
November 2024
Energy and Resources Institute, Charles Darwin University, Ellengowan Drive, Purple 12.01.08, Casuarina, NT 0810, Australia. Electronic address:
Contamination of chars with dioxin-like polychlorinated biphenyls (dl-PCB) significantly limits their use and hinders their deployment in the circular bioeconomy, specifically in applications that may lead to dietary exposure. Here, for the first time, we review the levels of contamination of chars produced from pyrolysis and hydrothermal carbonisation (HTC) with dl-PCB congeners. We conduct a detailed and critical examination of the role played by the processing parameters, such as temperature and residence time, and the reaction mechanisms, to detoxify the biomass under an oxygen-free atmosphere during its valorisation.
View Article and Find Full Text PDFAssessing the impact of conformational perturbants on folding and aggregation pathways of a β-barrel fold.
Biochem Biophys Res Commun
December 2024
Department of Biological Chemistry, School of Pharmacy and Biochemistry, University of Buenos Aires and Institute of Chemistry and Biological Physical Chemistry (IQUIFIB, UBA-CONICET), Junin 956, 1113, Buenos Aires, Argentina. Electronic address:
Here we explore the interplay between physical and chemical perturbants to unravel links among native folding, amorphous and ordered aggregation scenarios in IFABP (rat intestinal fatty acid binding protein). This small beta-barrel protein undergoes amyloid-like aggregation above 15 % v/v trifluoroethanol. Our aim was to address the influence of sub-aggregating TFE concentrations on the unfolding transitions of IFABP.
View Article and Find Full Text PDFUltrasound-assisted extraction of polysaccharide from Allium chinense G. Don epidermal waste: Evaluation of extraction mechanism, physicochemical properties, and bioactivities.
Ultrason Sonochem
December 2024
Department of Food Nutrition and Health, School of Medicine and Health, Faculty of Life Sciences and Medicine, Harbin Institute of Technology, Harbin 150001, PR China; Zhengzhou Research Institute, Harbin Institute of Technology, Zhengzhou 450003, PR China; National and Local Joint Engineering Laboratory for Synthesis, Transformation and Separation of Extreme Environmental Nutrients, Harbin Institute of Technology, Harbin 150001, PR China. Electronic address:
Allium chinense G. Don waste (ACGD) has an abundance of polysaccharides (ACGDP). Therefore, in this study, a method for extraction of ACGDP from ACGD by ultrasonic-assisted hot water extraction (UAE) based on ultrasonic cleaning equipment was developed.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!