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Design and implementation of an action plan for justice, equity, diversity, and inclusion within the Clinical Genome Resource.
Am J Hum Genet
January 2025
National Human Genome Research Institute, National Institutes of Health (NIH), Bethesda, MD, USA.
How might members of a large, multi-institutional research and resource consortium foster justice, equity, diversity, and inclusion as central to its mission, goals, governance, and culture? These four principles, often referred to as JEDI, can be aspirational-but to be operationalized, they must be supported by concrete actions, investments, and a persistent long-term commitment to the principles themselves, which often requires self-reflection and course correction. We present here the iterative design process implemented across the Clinical Genome Resource (ClinGen) that led to the development of an action plan to operationalize JEDI principles across three major domains, with specific deliverables and commitments dedicated to each. Active involvement of consortium leadership, buy-in from its members at all levels, and support from NIH program staff at pivotal stages were essential to the success of this effort.
View Article and Find Full Text PDFAlternative Formulations of Job Strain and Sleep Disturbances: A Longitudinal Study in the United States.
Am J Ind Med
January 2025
School of Nursing, University of California Los Angeles, Los Angeles, California, USA.
Background: Sleep disturbances are a major public health concern in the United States, leading to adverse health outcomes. In the working population, job strain has been identified as an important risk factor for sleep disturbances, but evidence from the United States remained limited. This study aimed to examine longitudinal associations between job strain and sleep disturbances in the United States, with a focus on the alternative formulations of job strain.
View Article and Find Full Text PDFRisk Adjustment in Medical Research: A Bird's Eye View.
J Korean Med Sci
November 2024
Independent Research Consultant, Shiraz, Iran.
Making correct decisions is of paramount importance in clinical medicine and health-related disciplines. Randomized clinical trials are considered the gold-standard type of study for the assessment of the efficacy of a treatment. However, conducting a randomized clinical trial is not always possible; observational studies should be conducted, instead.
View Article and Find Full Text PDFPrimary manipulation knowledge of objects is associated with the functional coupling of pMTG and aIPS.
Neuropsychologia
December 2024
Proaction Laboratory, Faculty of Psychology and Educational Sciences, University of Coimbra, Portugal; CINEICC, Faculty of Psychology and Educational Sciences, University of Coimbra, Portugal. Electronic address:
Correctly using hand-held tools and manipulable objects typically relies not only on sensory and motor-related processes, but also centrally on conceptual knowledge about how objects are typically used (e.g. grasping the handle of a kitchen knife rather than the blade avoids injury).
View Article and Find Full Text PDFHow Explainable Artificial Intelligence Can Increase or Decrease Clinicians' Trust in AI Applications in Health Care: Systematic Review.
JMIR AI
October 2024
Department of Social and Political Sciences, Bocconi University, Milano, Italy.
Background: Artificial intelligence (AI) has significant potential in clinical practice. However, its "black box" nature can lead clinicians to question its value. The challenge is to create sufficient trust for clinicians to feel comfortable using AI, but not so much that they defer to it even when it produces results that conflict with their clinical judgment in ways that lead to incorrect decisions.
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