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Two Sides of a Coin: Case Report of Unilateral Synangiosis and Contralateral Stroke Highlighting Consequences of Disease Progression and Efficacy of Revascularization in Sickle Cell Disease-Associated Moyamoya Syndrome. | LitMetric

AI Article Synopsis

  • - Moyamoya syndrome heightens stroke risk for patients with sickle cell disease, but performing revascularization surgery can help reduce this risk.
  • - Effective stroke management involves teamwork between hematology and neurosurgery to implement strategies that protect these patients.
  • - A complex case is discussed where a patient with sickle cell disease experienced stroke despite following established guidelines, highlighting gaps in our knowledge about how the disease progresses.

Article Abstract

Moyamoya syndrome increases the risk of stroke in sickle cell disease, but revascularization surgery can modify this risk. Collaborative management between hematology and neurosurgery offers effective strategies to reduce stroke risk in these patients. We describe a challenging case where a patient with sickle cell disease undergoing standard of care management as prescribed by the Stroke Prevention Trial in Sickle Cell Anemia and revascularization with pial synangiosis subsequently developed rapidly progressive disease in other cerebral vessels and suffered ischemic hemispheric stroke. This case not only demonstrates the success of management in accordance with the American Heart Association (AHA) and American Stroke Association (ASA) guidelines but also demonstrates critical areas where we lack understanding of disease progression.

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Source
http://dx.doi.org/10.1159/000521361DOI Listing

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