Both biochemical and mechanical signals coordinate all processes at the origin of the formation of functional organs, including tissue folding, cell shape, and differentiation. In this issue of Developmental Cell, Blonski et al. establish a direct consequence of epithelial monolayer folding on nuclear shape and gene expression.
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| http://dx.doi.org/10.1016/j.devcel.2021.11.013 | DOI Listing |
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