Background: In our previous report on Turkish COVID-19 patients requiring intensive care, the 24 patients in a single ICU were elderly and mortality was high. We extended our analysis to include patients admitted to ten ICUs.
Objectives: Report the demographics, clinical features, imaging findings, comorbidities, and outcomes in COVID-19 patients.
Design: Retrospective.
Setting: Intensive care unit.
Patients And Methods: The study includes patients with clinical and radiological confirmed or laboratory-confirmed COVID-19 infection who were admitted to ten ICUs between 15 March and 30 June 2020.
Main Outcome Measures: Clinical outcomes, therapies, and death during hospitalization SAMPLE SIZE: 974, including 571 males (58%).
Results: The median age (range) was 72 (21-101) years for patients who died (n=632, 64.9%) and 70 (16-99) years for patients who lived (n=432, 35.2%) (<.001). APACHE scores, and SOFA scores were higher in patients who died than in those who survived (<.001, both comparisons). Respiratory failure was the most common cause of hospitalization (82.5%), and respiratory failure on admission was associated with death (=.013). Most (n=719, 73.8%) underwent invasive mechanical ventilation therapy.
Conclusions: The majority of patients admitted to the ICU with a diagnosis of COVID-19 require respiratory support.
Limitations: Although the Turkish Ministry of Health made recommendations for the treatment of COVID-19 patients, patient management may not have been identical in all ten units.
Conflict Of Interest: None.
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http://dx.doi.org/10.5144/0256-4947.2021.318 | DOI Listing |
Front Biosci (Landmark Ed)
January 2025
Institute of Translational Medicine, Shanghai University, 200444 Shanghai, China.
Background: Dexamethasone has proven life-saving in severe acute respiratory syndrome (SARS) and COVID-19 cases. However, its systemic administration is accompanied by serious side effects. Inhalation delivery of dexamethasone (Dex) faces challenges such as low lung deposition, brief residence in the respiratory tract, and the pulmonary mucus barrier, limiting its clinical use.
View Article and Find Full Text PDFNurs Leadersh (Tor Ont)
June 2025
Current nursing shortages, particularly in complex practice or specialty areas, coupled with high attrition rates of both seasoned and new graduate nurses, have required nursing leaders to consider creative approaches to recruit, prepare and retain nurses in specialty areas. This article describes a collaborative partnership between post-secondary institutions and health authorities in one province to address the need to prepare and retain nurses in high-priority specialized areas, such as the intensive care unit or the emergency department. This partnership allows for a proactive connection that leverages the strengths and resources of both healthcare and educational institutions.
View Article and Find Full Text PDFNurs Leadersh (Tor Ont)
June 2025
Clinical Practice Leader Corporate Interprofessional Practice Lakeridge Health Durham Region, ON.
The integration of artificial intelligence (AI) into healthcare represents a paradigm shift with the potential to enhance patient care and streamline clinical operations. This commentary explores the Canadian perspective on key organizational considerations for nurse executives, emphasizing the critical role they play in fostering the establishment of AI governance structures and advancing the front-line adoption of AI in nursing practice. The discussion delves into five domains of consideration, analyzing recent developments and implications for nursing executives.
View Article and Find Full Text PDFNurs Leadersh (Tor Ont)
June 2025
Adjunct Professor School of Nursing, Faculty of Health Department of Community Health and Epidemiology, Faculty of Medicine Faculty of Graduate Studies Dalhousie University Halifax, NS.
Introduction: Black nurses are under-represented in the Canadian nursing workforce. A legacy of discrimination and systemic barriers reinforce the under-representation of Black nurses in the nursing workforce throughout the health system.
Objective: The objective of this study was to identify and describe organizational initiatives for the recruitment, retention and advancement of Black nurses in the healthcare system.
Br J Hosp Med (Lond)
January 2025
Department of Obstetrics and Gynecology, The First Clinical Medical College of Three Gorges University, Yichang Central People's Hospital, Yichang, Hubei, China.
Gestational diabetes mellitus (GDM) is a common complication during pregnancy. This retrospective study investigates the correlation between umbilical blood flow index and maternal-fetal outcomes in pregnant women with GDM, aiming to contribute to evidence-based risk assessment and management strategy in this high-risk obstetric population. This retrospective study recruited 119 pregnant women with GDM who were admitted to the Yichang Central People's Hospital, between January 2022 and January 2024.
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