The heart, an endocrine gland: Natriuretic peptides.

Ann Endocrinol (Paris)

Endocrinology, Diabetology and Metabolism Department, Université de Lille, CHU de Lille, Lille, France; Inserm U1190, 59000 Lille, France. Electronic address:

Published: February 2022

The natriuretic peptide family consists of three biologically active peptides: atrial natriuretic peptide (ANP), brain (or B-type) natriuretic peptide (BNP), and C-type natriuretic peptide (CNP). ANP and BNP, secreted by the heart, act as cardiac hormones, whereas CNP is an endothelial peptide. The aim of this manuscript is to review the production, action mechanisms, effects and clinical applications of natriuretic peptides.

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http://dx.doi.org/10.1016/j.ando.2021.11.006DOI Listing

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