Purpose: To investigate the prevalence of echogenicity in the fetal gallbladder (EFG) and to present prenatal sonographic findings and their postnatal outcomes.
Materials And Methods: We performed a retrospective study within 17420 pregnant women during a 66-month period. Fetuses with an incidental finding of EFG in their 2nd or 3rd trimester of pregnancy were followed until birth per two weeks with sonographic examinations.
Results: Out of 5977 fetuses, 44 fetuses were found to have EFG with a prevalence of 0.74%. Nine (20%) of 44 fetuses had single echogenicity, 25 (56%) had multiple echogenicities, 10 (22%) had sludge-like echogenicities. In Doppler sonography, 28 fetuses with EFG exhibited twinkling artifacts; however, none of the echogenicities had obvious acoustic shadowing. All of the cases were resolved either in utero or after birth before 10 months of age.
Conclusion: EFG is a late third-trimester phenomenon with a prevalence of 0.74%. Most EFGs presented as twinkling artifacts, suggesting they had a cholesterol component.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/jcu.23092 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Identification of de-novo CREBBP gene variants in patients with Rubinstein-Taybi syndrome.
Psychiatr Genet
February 2025
Department of Obstetrics.
Rubinstein-Taybi syndrome (RSTS) is an autosomal dominant genetic disease characterized by growth retardation, psychomotor retardation, and distinctive facial features. It is primarily caused by mutations in CREBBP or EP300. In this study, we aimed to describe the clinical manifestations and genetic analyses of two cases with RSTS.
View Article and Find Full Text PDFPostnatal Outcome After Ultrasound Findings of an Abnormal Fetal Gallbladder: A Systematic Review and Meta-Analysis.
Prenat Diagn
December 2024
Fetal Medicine Unit, Elizabeth Garrett Anderson Wing, University College Hospital, London, UK.
Objective: To describe postnatal outcome following the prenatal diagnosis of an abnormal fetal gallbladder.
Methods: We conducted a systematic review of studies from January 1980 to January 2023 that described FGB abnormalities, which included agenesis or non-visualisation, abnormal content presence of sludge, abnormal shape or size and abnormal position, and postnatal outcome to determine the association with pathology.
Results: In 51 studies, 842 fetuses had abnormal FGB.
Gallbladder Perforation in a Pregnant Patient: A Case Report and Considerations of Surgical Approach.
Cureus
November 2024
Human Anatomy Department, Clinical-Surgical Research Group (GICQx), Universidad Autónoma de Nuevo León, Monterrey, MEX.
Gallbladder disease is a frequent indication for non-obstetric surgical intervention during pregnancy. Gallbladder perforation (GBP) during pregnancy is an uncommon but severe pathology that usually requires immediate attention, and it represents a challenge for surgeons. We present the case of a GBP in a pregnant patient alongside a discussion of available surgical approaches.
View Article and Find Full Text PDFPrenatal genetic detection in foetus with gallbladder size anomalies: cohort study and systematic review of the literature.
Ann Med
December 2025
Medical Genetics Center, Guangdong Women and Children Hospital, Guangzhou, China.
Objectives: The aim of the study was to evaluate the detection rate of genetic abnormalities in cases of foetal gallbladder (FGB) size abnormalities to determine whether these abnormalities justify prenatal diagnosis.
Methods: Two hundred and twenty-seven foetuses with gallbladder (GB) size anomalies who underwent prenatal diagnosis between January 2015 and June 2024 were included in the study. All these patients underwent chromosomal microarray and/or karyotyping, and 37 cases also underwent whole exome sequencing (WES).
Unique presentation of perforated gallbladder and gangrene in third trimester pregnancy: management and other considerations.
BMJ Case Rep
December 2024
General Surgery, Texas Tech University Health Science Center School of Medicine, Amarillo, Texas, USA.
Acute cholecystitis during pregnancy presents significant risks, requiring careful management to balance maternal and fetal health. Conflicting viewpoints exist on conservative versus surgical treatment, particularly in the third trimester. Here, we present a case of a woman in her early 40s at 34 weeks of gestational age with acute cholecystitis and signs of preterm labour.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!