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http://dx.doi.org/10.1097/QAD.0000000000003076 | DOI Listing |
Antibiotics (Basel)
January 2025
Department of Biotechnology, Ghent University, Valentin Vaerwyckweg 1, 9000 Gent, Belgium.
Phage tail-like bacteriocins, or tailocins, provide a competitive advantage to producer cells by killing closely related bacteria. Morphologically similar to headless phages, their narrow target specificity is determined by receptor-binding proteins (RBPs). While RBP engineering has been used to alter the target range of a selected R2 tailocin from , the process is labor-intensive, limiting broader application.
View Article and Find Full Text PDFMicrob Pathog
January 2025
Uttarakhand State Council for Science and Technology (UCOST), Vigyan Dham, Jhajra, Dehradun, India 248007.
Nowadays, antimicrobial resistance and foodborne burden are a prevalent global concern for human health and sustainable development. In this context, this study aimed to investigate the effect of Bacopa monnieri (L.) Pennell extract against pathogenic foodborne bacteria (Escherichia coli, Staphylococcus aureus, and Listeria monocytogenes).
View Article and Find Full Text PDFFront Sports Act Living
January 2025
'Fundación Sanitas' Chair for Inclusive Sport Studies (CEDI), Department of Health and Human Performance, AFIPE Research Group, Faculty of Physical Activity and Sport Sciences-INEF, Universidad Politécnica de Madrid, Madrid, Spain.
Introduction: Women with disabilities may experience particular difficulties in starting and developing in sport, also in the Paralympic context. Although a great deal of research has been conducted with high-performance athletes, relatively few studies have focused on athletes with disabilities, especially Paralympic women using person-first approaches. Thus, the main objective of this study is to understand, through the experience and opinion of a Paralympian female athlete, how these athletes reach their full potential, identifying the elements and initiatives that can influence (whether positively or negatively) their sporting trajectory and developmental milestones.
View Article and Find Full Text PDFAdv Sci (Weinh)
January 2025
Department of Human Cell Biology and Genetics, Joint Laboratory of Guangdong-Hong Kong Universities for Vascular Homeostasis and Diseases, School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong, 518055, China.
Recent advancements in microRNAs (miRNAs) research have revealed their key roles in both normal physiological processes and pathological conditions, leading to potential applications in diagnostics and therapeutics. However, the path forward is fraught with several scientific and technical challenges. This review article briefly explores the milestones of the discovery, biogenesis, functions, and application for clinical diagnostic and therapeutic strategies of miRNAs.
View Article and Find Full Text PDFEnviron Microbiome
January 2025
Université de Caen Normandie, Laboratoire MERSEA UR 7482, Centre de Recherches en Environnement Côtier, 14530, Luc-sur-Mer, France.
Background: Estuaries are complex ecosystems linking river and marine environments, where microorganisms play a key role in maintaining ecosystem functions. In the present study, we investigated monthly 8 sites at two depth layers and over a one-year period the bacterial and eukaryotic community dynamics along the Seine macrotidal estuary (Normandy, France). To date, the taxonomy of the microbial diversity present in this anthropized estuary remains elusive and the drivers of the microbial community structure are still unknown.
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