Canine sacroiliac (SI) joint subluxation or luxation is most commonly diagnosed based on qualitative radiographic assessments. Aims of this two-part, retrospective, diagnostic accuracy, pilot study were to develop and evaluate a novel quantitative method based on measuring the angle between a line connecting the iliac wings and parallel lines across three anatomical landmarks (cranial endplate of L7, caudal endplate of L6, cranial endplate of L6) on a single ventrodorsal radiograph. For the first part of the study, angle measurements from a single observer were compared for 20 normal canine pelvic radiographs and 20 pelvic radiographs with SI luxation or subluxation. Mean values significantly differed between datasets (P < 0.001). The angles for the normal pelves ranged from 0.6° to 1.5°, while abnormal angles ranged from 3.8° to 7.1°. For the second part of the study, a dataset of 25 normal and 25 abnormal canine pelvic radiographs was evaluated using the novel technique by three blinded readers with varying levels of expertise at two different time points. There was excellent reliability among the three readers with an intraclass correlation (ICC) value of 0.90 and an excellent agreement between day 0 and day 30 readings with an ICC value of 0.91. It was also determined that a cut-off angle of 2.0°, using the line parallel to the cranial endplate of L6, provided overall the best accuracy, sensitivity, and specificity to differentiate normal versus abnormal pelves. These findings may be helpful for clinical cases with equivocal diagnoses and for future development of automated diagnostic tools.

Download full-text PDF

Source
http://dx.doi.org/10.1111/vru.13045DOI Listing

Publication Analysis

Top Keywords

novel quantitative
8
normal canine
8
canine sacroiliac
8
subluxation luxation
8
pilot study
8
cranial endplate
8
pelvic radiographs
8
repeatability accuracy
4
accuracy novel
4
quantitative radiographic
4

Similar Publications

Dissecting the Genetic Basis of Preharvest Sprouting in Rice Using a Genome-Wide Association Study.

J Agric Food Chem

January 2025

Collaborative Innovation Center of Regional Modern Agriculture and Environment Protection Co-constructed By the Province and Ministry, Huaiyin Normal University, Huai'an 223300, China.

Preharvest sprouting (PHS) is an unfavorable trait in cereal crops that significantly reduces grain yield and quality. However, the regulatory mechanisms underlying this complex trait are still largely unknown. Here, 276 rice accessions from the 3000 Rice Genomes Project were used to perform a genome-wide association study.

View Article and Find Full Text PDF

Background: Most cancer survivors have multiple cardiovascular risk factors, increasing their risk of poor cardiovascular and cancer outcomes. The Automated Heart-Health Assessment (AH-HA) tool is a novel electronic health record clinical decision support tool based on the American Heart Association's Life's Simple 7 cardiovascular health (CVH) metrics to promote CVH assessment and discussion in outpatient oncology. Before proceeding to future implementation trials, it is critical to establish the acceptability of the tool among providers and survivors.

View Article and Find Full Text PDF

Background: Research into the intratumoral microenvironment in lymphoma has been escalated along with improved survival and new targeted therapies with an intent to refine risk stratification and prognostication. Various studies have reported significance of quantitative DCE-MRI parameters for predicting biological behaviour of various tumors. This study is an endeavour to supplement the existing literature on quantitative DCE-MRI in nodal lymphoma.

View Article and Find Full Text PDF

Integrative Transcriptome-Wide Association Study With Expression Quantitative Trait Loci Colocalization Identifies a Causal VAMP8 Variant for Nasopharyngeal Carcinoma Susceptibility.

Adv Sci (Weinh)

January 2025

State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Sun Yat-sen University, Guangzhou, 510060, P. R. China.

Nasopharyngeal carcinoma (NPC) is an Asia-prevalent malignancy, yet its genetic underpinnings remain incompletely understood. Here, a transcriptome-wide association study (TWAS) is conducted on NPC, leveraging gene expression prediction models based on epithelial tissues and genome-wide association study (GWAS) summary statistics from 1577 NPC cases and 6359 controls of southern Chinese descent. The TWAS identifies VAMP8 on chromosome 2p11.

View Article and Find Full Text PDF

Barley yellow dwarf (BYD) is one of the most serious viral diseases in cereal crops worldwide. Identification of quantitative trait loci (QTLs) underlining wheat resistance to barley yellow dwarf virus (BYDV) is essential for breeding BYDV-tolerant wheat cultivars. In this study, a recombinant inbred line (RIL) population was developed from the cross between Jagger (PI 593688) and a Jagger mutant (JagMut1095).

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!