To compare the safety of the non-ophthalmic viscosurgical device (OVD) technique with that of the minimum OVD technique in EVO Implantable Collamer Lens (EVO-ICL) implantation. A total of 180 eyes of 90 consecutive patients were enrolled in the study, of which 100 eyes of 50 patients were treated with non-OVD technique, with a 55% success rate. The remaining 80 eyes of 40 patients were treated with min-OVD technique, so they were classified into the min-OVD group. Preoperative and postoperative intraocular pressure (IOP) measurements were collected and analyzed at 1, 2, 3, and 24 h. Visual acuity, corneal endothelial cell density (ECD), and corneal densitometry 24 h postoperatively were evaluated. No significant difference was found in visual outcomes ( = 0.54) or ECD ( = 0.78) between the two groups. The operation time was significantly shorter in the non-OVD group ( < 0.0001). The IOP was significantly higher at 1 h ( < 0.0001), 2 h ( < 0.0001) and 3 h ( = 0.0045) postoperatively in the min-OVD group. The non-OVD group had significantly lower IOP than the min-OVD group at 1 h ( = 0.01) and 2 h ( = 0.013) postoperatively. The temporal corneal densitometry in the non-OVD group were significantly lower than those in the minimum group ( = 0.0063) 1 day after surgery. The non-OVD technique is safe and efficient for ICL implantation. It can be a safer method of ICL implantation in that it completely eliminates ophthalmic viscoelastic devices related complications without causing additional complications in short term.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635781 | PMC |
http://dx.doi.org/10.3389/fmed.2021.764653 | DOI Listing |
BMC Ophthalmol
January 2025
Department of Ophthalmology and Visual Sciences, McGill University, 5252 Maisonneuve Blvd W, 4th floor,, Montreal, Québec, H4A 3S5, Canada.
Objective: To assess refractive and visual outcomes of a spherical Implantable Collamer Lens (ICL) followed by planned postoperative adjunctive laser-assisted in situ keratomileusis (LASIK) in the treatment of high compound hyperopic astigmatism.
Methods: In this prospective, multi-center, multi-surgeon, single-arm trial, eyes with ≥ 3.50 D hyperopia and ≥ 2.
Ann Med
December 2025
Department of Ophthalmology, West China Hospital of Sichuan University, Chengdu City, China.
Objectives: The objective of the investigation is to examine the long term efficacy, safety, and predictability of ICL-V4c implantation for high and super-high myopic patients in order to provide reliable guidance for the selection of refractive surgical procedures.
Methods: We reviewed 125 eyes from 64 patients who implanted ICL-V4c at the Refractive Surgery Center of West China Hospital in Chengdu, China, between May 2015 and January 2017. These eyes were divided into two groups based on their preoperative spherical equivalent (SE) degree: high myopia (≥ -10D) and super-high myopia groups (< -10D).
Heliyon
January 2025
Department of Cataract, Shanxi Eye Hospital Affiliated to Shanxi Medical University, Taiyuan, Shanxi, 030001, China.
Purpose: Using a fully automated multitask deep learning method, which enabled simultaneous segmentation and quantification of all major anterior segment structures with swept-source optical coherence tomography (SS-OCT), we aimed to investigate the three-dimensional (3D) alterations in iris morphology before and after implantable collamer lens (ICL) surgery.
Methods: All enrolled patients underwent anterior segment SS-OCT (ANTERION) within one week before and after ICL surgery. A multitask network automatically performed iris SS-OCT image segmentation and quantitative measurements of 3D iris morphology (iris thickness and volume of the inner 1-mm annular area and the outer 1-2-mm annular area, iris curvature [I-Curve], and iris smooth index [SI]).
BMC Ophthalmol
January 2025
Department of Refractive Surgery, Guangzhou Aier Eye Hospital, Jinan University, Guangzhou City, Guangdong Province, 510000, China.
Purpose: To evaluate the impact of Implantable Collamer Lens (ICL) implantation on anterior chamber angle parameters and posterior segment structures in highly myopic eyes and explore potential correlations between these changes. The study aimed to assess alterations in superficial and deep vessel density (SVD, DVD), foveal avascular zone (FAZ) area, and retinal nerve fiber layer (RNFL) thickness to clarify the safety profile of ICL implantation.
Methods: Prospective observational study, included 36 highly myopic eyes undergoing ICL implantation in surgery group and 23 non-surgical control eyes in non-surgery group.
Int J Surg Case Rep
January 2025
King Khaled Eye Specialist Hospital, Riyadh, Kingdom of Saudi Arabia. Electronic address:
Introduction: Implantable collamer lens (ICL) is a posterior chamber phakic intraocular lens. It is usually indicated for high refractive error correction that cannot be treated by laser vision correction due to physical limitations.
Case Presentation: 39 years old male with a past ocular history of keratoconus underwent astigmatic keratotomy followed by crosslinking in both eyes a couple of years later due to signs of corneal ectasia progression.
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