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http://dx.doi.org/10.3389/fphar.2021.799020 | DOI Listing |
Pediatr Neonatol
January 2025
Division of Pediatric Nephrology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, 833, Taiwan; College of Medicine, Chang Gung University, Taoyuan, 330, Taiwan; Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, 833, Taiwan. Electronic address:
JACC Heart Fail
January 2025
Division of Cardiovascular Medicine, Indiana University, Indianapolis, Indiana, USA. Electronic address:
J Clin Neurol
January 2025
Dizziness Center, Clinical Neuroscience Center, Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea.
J Clin Neurol
January 2025
Department of Neurology, Hanyang University College of Medicine, Seoul, Korea.
Eur J Neurosci
January 2025
Department of Biology, Concordia University, Montreal, QC, Canada.
Through the lens of preclinical research on substance use disorders (SUD), I propose a reflection aimed at re-evaluating animal models in neuroscience, with a focus on ecological relevance. While rodent models have provided valuable insights into the neurobiology of SUD, the field currently faces a validation crisis, with findings often failing to translate into effective human treatments. Originally designed to address the lack of reproducibility in animal studies, the current global gold standard of rigorous standardization has led to increasingly controlled environments.
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