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Optimal Duration of Antibiotic Therapy for Primary Osteomyelitis Discitis: A Systematic Review and Network Meta-Analysis.
Spine (Phila Pa 1976)
December 2024
University of Missouri-Kansas City School of Medicine, 2411 Holmes St, Kansas City, MO 64108.
Study Design: Systematic Review and Network-Meta-analysis.
Purpose: This study aimed to systematically review the literature on management of primary osteomyelitis discitis and perform a network meta-analysis comparing the efficacy of different antibiotic treatment durations.
Background: Primary osteomyelitis discitis is a challenging condition with varying management strategies.
Seasonal trends of pyogenic spondylodiscitis in Japan: a nationwide inpatient database study.
Int J Infect Dis
December 2024
Department of Orthopedic Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
Objectives: The aims of this study were 1) to investigate seasonal epidemiological variations of pyogenic spondylodiscitis, including Methicillin-resistant Staphylococcus aureus (MRSA) infection, in Japan, and 2) to evaluate associated inpatient outcomes.
Methods: We performed a retrospective nationwide study using data from the Japanese Diagnosis Procedure Combination (DPC) inpatient database, covering the period from 2010 to 2022. The parameters assessed were seasonal incidence, demographic characteristics, inpatient mortality, complications, and medical costs.
Management Outcomes after Image-guided Percutaneous Biopsy for Suspected Vertebral Osteomyelitis-Discitis.
AJNR Am J Neuroradiol
December 2024
From the Department of Radiology (DGM., MVS., GMS., REG., JSR., TJR.) Mayo Clinic, Phoenix, AZ, USA; Department of Radiology (FED.), Mayo Clinic, Rochester, MN, USA. Department of Radiology (EHM.), Mayo Clinic, Jacksonville, FL, USA.
Background And Purpose: Studies show a modest yield for image-guided biopsy of suspected vertebral osteomyelitis-discitis. Many studies evaluate factors to improve diagnostic yield, and few studies assess how biopsy results impact clinical management. We aim to evaluate the impact of biopsy results on clinical management in suspected vertebral osteomyelitis-discitis.
View Article and Find Full Text PDFVertebral osteomyelitis in patients with an underlying malignancy or chronic kidney disease - who is at higher risk for adverse outcome?
Infection
December 2024
Department I of Internal Medicine, Division of Infectious Diseases, University of Cologne, Cologne, Germany.
Purpose: Patients with vertebral osteomyelitis (VO) and comorbidities, notably chronic kidney disease (CKD), are at risk of early mortality. The aim of this study was to compare characteristics and outcomes of VO patients with an underlying malignancy (ONCO) to VO patients with CKD and VO patients without comorbidities (CONTROL).
Methods: We performed a retrospective analysis of data which was prospectively collected between 2008 and 2020.
Citrobacter youngae nosocomial bacteremia from postoperative pyogenic spondylodiscitis after a minimally invasive spinal surgery.
BMC Infect Dis
December 2024
108 Military Central Hospital, Vietnamese - German Center for Medical Research (VG-CARE), N 1, Tran Hung Dao Str., Hai Ba Trung Dist, Hanoi, 1000, Vietnam.
Citrobacter youngae (C. youngae) was first described in 1993, and data suggesting that human diseases caused by this bacterium remain scarce. Reports on C.
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