Infectious diarrhea in China showed a significant pattern. Many researchers have tried to reveal the drivers, yet usually only meteorological factors were taken into consideration. Furthermore, the diarrheal data they analyzed were incomplete and the algorithms they exploited were inefficient of adapting realistic relationships. Here, we investigate the impacts of meteorological and social factors on the number of infectious diarrhea cases in China. A machine learning algorithm called the Random Forest is utilized. Our results demonstrate that nearly half of infectious diarrhea occurred among children under 5 years old. Generally speaking, increasing temperature or relative humidity leads to increased cases of infectious diarrhea in China. Nevertheless, people from different age groups or different regions own different sensitivities to meteorological factors. The weight of feces that are harmfully treated could be a possible reason for infectious diarrhea of the elderly as well as children under 5 years old. These findings indicate that infectious diarrhea prevention for children under 5 years old remains a primary task in China. Personalized prevention countermeasures ought to be provided to different age groups and different regions. It is essential to bring the weight of feces that are harmfully treated to the forefront when considering infectious diarrhea prevention.
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http://dx.doi.org/10.1038/s41598-021-00932-0 | DOI Listing |
Sci Total Environ
January 2025
Gangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA.
Poor water, sanitation, and hygiene (WASH) are the primary risks of exposure to enteric viral infection. Our study aimed to describe the role of WASH conditions and practices as risk factors for enteric viral infections in children under 5. Literature on the risk factors associated with all-cause diarrhea masks the taxa-specific drivers of diarrhea from specific pathogens, limiting the application of relevant control strategies.
View Article and Find Full Text PDFBackground: Existing therapeutic approaches in Alzheimer's disease (AD) targeting beta-amyloid and tau proteins have shown limited success. Shigellosis, an intestinal infection caused by Shigella, is capable of colonizing the human intestinal epithelium and has been associated with focal adhesions. Rap1 signaling is associated with cancer and cell adhesions.
View Article and Find Full Text PDFCan Vet J
January 2025
Department of Comparative, Diagnostic, and Population Medicine, College of Veterinary Medicine, University of Florida, 2015 SW 16th Avenue, Gainesville, Florida 32608, USA (Whitman); Gulf Coast Veterinary Specialists, 8042 Katy Freeway, Houston, Texas 77024, USA (Wilson); Department of Small Animal Clinical Sciences, Texas A&M School of Veterinary Medicine and Biomedical Sciences, 4474 TAMU, College Station, Texas 77843, USA (Heseltine).
Canine systemic protothecosis is an uncommon disease caused by spp., which are saprophytic algae occurring ubiquitously in nature. Infection occurs most commonly in immunocompromised animals.
View Article and Find Full Text PDFJ Am Nutr Assoc
January 2025
Department of Gastroenterology, Shaoxing People's Hospital, Shaoxing, China.
Objective: We explored potential relationships between dietary live microbe intake and chronic diarrhea (CD) and fecal incontinence (FI).
Methods: We conducted a cross-sectional retrospective study based on the National Health and Nutrition Examination Survey (NHANES) database. Participants were categorized into three groups according to the Sanders classification system (low, medium, and high dietary live microbe groups).
Therap Adv Gastroenterol
January 2025
Operative Unit of Clinical Pharmacology and Pharmacovigilance, Renato Dulbecco University Hospital, Catanzaro, Italy.
Acute infectious diarrhea (AID) represents an important clinical entity both regarding morbidity and mortality rates, even in industrialized countries, and it leads to one of the major public health burdens, among gastroenterological diseases, with significant healthcare costs. Oral rehydration solution is the cornerstone of the therapy, but despite its proven efficacy in avoiding dehydration, it is still underused as it does not reduce the duration of diarrhea; hence, it is perceived as ineffective by caregivers. In this narrative review, we collected literature regarding the use of racecadotril, deeply discussing its role in the treatment of AID in both adults and children.
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