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Dapsone-induced haemolysis among leprosy patients on MDT from an endemic area of central India.
J Family Med Prim Care
September 2024
Department of Dermatology, All India Institute of Medical Sciences, Deoghar, Jharkhand, India.
Background And Aim: Haemolysis due to dapsone as a part of MDT in leprosy patients has been long recognized. However, the frequency and severity of this side effect and factors associated with it have not been well documented. We planned to determine the frequency of dapsone-induced haemolysis in leprosy patients on MDT and various risk factors associated with it.
View Article and Find Full Text PDFDapsone-induced methemoglobinemia and hemolysis in a woman without G6PD deficiency presenting with idiopathic urticaria.
Hematology
December 2022
Department of Laboratory Medicine, University of California San Francisco, San Francisco, CA, USA.
Background: The appearance of bite cells associated with methemoglobinemia can be caused by oxidizing drugs such as dapsone in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency or high drug serum levels. Bite cells are often pathognomonic for oxidant injury in patients with G6PD deficiency and suggest active hemolysis.
Case Presentation: We report a case of a woman with no prior history of G6PD deficiency who presented with anemia, methemoglobinemia and bite cells on peripheral blood smear after dapsone therapy for new onset idiopathic urticaria.
Dapsone-Induced Hematologic Abnormalities in Dermatologic Patients.
Skinmed
February 2022
Department of Dermatology, Tulane University School of Medicine, New Orleans LA.
A Case of Dapsone-induced Mild Methemoglobinemia with Dyspnea and Cyanosis.
Acta Dermatovenerol Croat
December 2020
Hisayoshi Imanishi, MD, PhD, Division of Dermatology, Daito Central Hospital, 2-1-11 Ono, Daito, Osaka 574-0042, Japan;
Dear Editor, Dapsone is a dual-function drug with antimicrobial and antiprotozoal effects and anti-inflammatory features (1). In dermatology, it is a first choice for conditions such as leprosy, IgA pemphigus, dermatitis herpetiformis, and linear IgA bullous dermatosis, or an adjunctive treatment for, e.g.
View Article and Find Full Text PDFDapsone-Induced Hemolytic Anemia in Multiple Myeloma: Case Report of Various Differential Diagnoses.
Clin Lymphoma Myeloma Leuk
November 2020
Department of Medicine I (Hematology, Oncology, and Stem Cell Transplantation), Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany. Electronic address:
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