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Synthesis of taurine-Cu(PO) hybrid nanoflower and their peroxidase-mimic and antimicrobial properties. | LitMetric

AI Article Synopsis

  • The study reports the creation of taurine-incorporated hybrid nanoflowers (thNFs) that demonstrate peroxidase-mimicking and antimicrobial activities when exposed to hydrogen peroxide (HO).
  • The formation of thNFs was explored for the first time using non-enzyme molecules, with factors like taurine concentration, metal ion types (Cu, Fe), and pH being systematically analyzed.
  • Characterization techniques confirmed the thNFs' porous structure and transition metal ions, which enhance their effectiveness, making them potential alternatives to traditional enzymes for various applications in medicine and industry.

Article Abstract

Herein, we report the synthesis of taurine incorporated (sulfur containing organic molecule derived from methionine and cysteine) hybrid nanoflowers (thNFs) with an intrinsic peroxidase-mimic and antimicrobial activities in the presence of HO. Formation of thNFs using non-enzyme molecules was for the first time and systematically studied as a function of the taurine concentration, types of metal ions (Cu, Fe and Fe) and pH values of reaction solution. The peroxidase like activities of thNFs rely on Fenton-like reaction against guaiacol used as a model substrate. The efficiency of Fenton reaction can be attributed to porous structure and presence of ions of transition elements in the thNFs. The thNFs were further characterized using FTIR, XRD, SEM and EDX. The thNFs also showed remarkable antimicrobial properties against S. aureus, E. coli, B. cereus and C. albicans. We claim that nonprotein-based NFs can be considered as new generation nano-biocatalysts as an alternative to enzymes and can be used in various medicinal, biochemical, immunological, biotechnological, and industrial applications.

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Source
http://dx.doi.org/10.1016/j.jbiotec.2021.11.009DOI Listing

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