Objective: This study comprehensively reviewed clinical trials that investigated the effect of immediate dentin sealing (IDS) technique on postoperative sensitivity (POS) and clinical performance of indirect restorations.
Materials And Methods: The systematic review was conducted according to the preferred reporting items for systematic reviews and meta-analyses statement, and was guided by the PICOS strategy. Clinical trials in which adult patients received at least one indirect restoration cemented with IDS approach and one restoration cemented following the delayed dentin sealing (DDS) were considered.
Results: Following title screening and full-text reading, four studies met the inclusion criteria and were included for qualitative synthesis, while two studies were selected for quantitative synthesis. According to Risk of bias-2 tool, two studies were classified as "some concerns" for the outcome POS. No statistically significant differences were found between teeth restored with indirect restorations using the IDS and DDS approach for POS (p > 0.05), neither at the baseline (very low certainty of evidence according to GRADE) nor after 2 years of follow-up (low certainty of evidence according to GRADE).
Conclusion: There is low-certainty evidence that IDS does not reduce POS in teeth restored with indirect restorations.
Clinical Significance: There is no clinical evidence to favor IDS over DDS when restoring teeth with indirect restorations.
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http://dx.doi.org/10.1111/jerd.12841 | DOI Listing |
Bioengineering (Basel)
December 2024
Department of Biomaterials and Regenerative Dental Medicine, University Maryland School of Dentistry, Baltimore, MD 21201, USA.
Traditional pulp-capping materials like mineral trioxide aggregate (MTA) offer excellent biocompatibility and sealing, but limitations such as prolonged setting time, low bioactivity, and high costs persist. Metformin, with its potential in craniofacial regeneration, could enhance dentin synthesis by targeting pulp cells. This study aimed to: (1) develop a calcium phosphate cement with chitosan (CPCC) with improved physio-mechanical properties; (2) incorporate metformin (CPCC-Met) to assess release; and (3) evaluate human dental pulp stem cells (hDPSCs) response.
View Article and Find Full Text PDFAm J Case Rep
January 2025
Department of Restorative Dentistry, College of Dentistry, Umm Al-Qura University, Mekkah, Saudi Arabia.
BACKGROUND Internal root resorption (IRR) is a rare dental condition characterized by the progressive resorption of dentin within the root canal, often resulting from infection, trauma, or orthodontic treatment. When IRR progresses to perforation, it creates a communication pathway with periodontal tissues, necessitating effective endodontic therapy and perforation repair. Bioceramic sealers, known for their biocompatibility and flowability, have emerged as a promising alternative to traditional materials for filling and sealing the root canal system.
View Article and Find Full Text PDFJ Esthet Restor Dent
January 2025
Operative Department, Faculty of Dentistry, Mansoura University, Mansoura, Egypt.
Objective: To investigate the effect of cervical margin relocation with four different injectable restorative materials on the fracture resistance of molars receiving mesio-occluso-distal CAD/CAM nanoceramic onlay restorations.
Materials And Methods: One hundred and five sound mandibular molars received a standardized mesio-occluso-distal onlay preparation, with cervical margins located 2 mm apical to the cemento-enamel junction. The molars were randomly allocated into five groups (n = 21) according to the cervical relocating materials used: Group I had no cervical margin relocation; Group II used a highly viscous glass ionomer; Group III used a highly-filled injectable resin composite; Group IV used a resin-modified glass ionomer; and Group V used a bioactive ionic resin.
J Mater Chem B
January 2025
Oral Implant Centre, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, People's Republic of China.
Dentin hypersensitivity is primarily caused by the exposure of dentinal tubules due to various factors, so the key to treatment is to effectively seal these exposed tubules. However, traditional dentinal tubule sealants used in clinical practice often fail to adhere securely to the tubule surface when exposed to external stimuli, resulting in a recurrence of sensitivity. In this study, we developed a silicon micromotor that moved autonomously and loaded with silver nanoparticles and a photosensitive adhesive for dentin sensitivity therapy.
View Article and Find Full Text PDFCureus
December 2024
Oral and Maxillofacial Surgery, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Pune, IND.
Introduction Endodontic re-infections primarily occur due to the ingress of bacteria and their toxins through an incomplete seal following obturation. A variety of sealers have been developed to achieve effective integration with the different obturation materials and dentinal tubules. To choose the right endodontic sealer and application for each clinical instance, one must be aware of the attributes of the various sealers commonly used in clinical practice.
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