Aim: To investigate whether fourth ventricle dimensions and tentorial angulation differ in a healthy control population in our evaluation of patients with CM-1 malformation using MRI.
Material And Methods: The radiological and demographic data from 251 patients with CM-1 followed in our clinic between 2014 and 2019 were compared with data from 273 persons in a healthy control group. Fourth ventricle dimensions, amount of cerebellar tonsillar herniation, and tentorium twinning angle were measured. Statistical analysis was performed.
Results: The mean tentorial twinning angle, craniocaudal length, and anteroposterior length of the fourth ventricle were significantly greater than the mean of the same measurements in the healthy control group. In addition, in a subgroup analysis conducted according to treatment modalities of patients with CM-1, the length between the bilateral recesses of the fourth ventricle was found to be statistically significantly greater in the subgroup of patients who underwent surgery compared with those in the nonsurgical subgroup.
Conclusion: Fourth ventricle enlargement is a radiographic finding in patients with CM-1. Studies evaluating clinical presentation, severity, and outcome after treatment will be useful in revealing the importance of this entity.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.5137/1019-5149.JTN.35404-21.2 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Subdural hematoma as a complication of endoscopic third ventriculostomy in a pediatric patient: a case report and literature review.
Childs Nerv Syst
January 2025
Department of Neurosurgery, Hospital de São José, ULS São José, Lisbon, Portugal.
Background: Subdural hematoma (SDH) typically occurs due to traumatic brain injury but can arise as a rare complication of procedures like endoscopic third ventriculostomy (ETV).
Case Presentation: We report an unusual case in a 9-year-old male with previous resection of a fourth-ventricle ependymoma at 2 years of age. Seven years post-surgery, he presented with worsening hydrocephalus and underwent ETV.
Real-Time 2D Phase-Contrast MRI to Assess Cardiac- and Respiratory-Driven CSF Movement in Normal Pressure Hydrocephalus.
J Neuroimaging
December 2024
Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Background And Purpose: In idiopathic normal pressure hydrocephalus (iNPH) patients, cerebrospinal fluid (CSF) flow is typically evaluated with a cardiac-gated two-dimensional (2D) phase-contrast (PC) MRI through the cerebral aqueduct. This approach is limited by the evaluation of a single location and does not account for respiration effects on flow. In this study, we quantified the cardiac and respiratory contributions to CSF movement at multiple intracranial locations using a real-time 2D PC-MRI and evaluated the diagnostic value of CSF dynamics biomarkers in classifying iNPH patients.
View Article and Find Full Text PDFPCSK9 inhibitor alleviates experimental pulmonary fibrosis-induced pulmonary hypertension via attenuating epithelial-mesenchymal transition by suppressing Wnt/β-catenin signaling and .
Front Med (Lausanne)
December 2024
Medical College of Soochow University, Suzhou, Jiangsu, China.
Background: The co-occurrence of pulmonary hypertension (PH) in patients with pulmonary fibrosis (PF) is linked to a more unfavorable prognosis and increased mortality compared to PF cases without PH. Early intervention and comprehensive management are pivotal for improving survival outcomes. Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a protein essential in cholesterol metabolism.
View Article and Find Full Text PDFMRI appearance of Bochdalek's flower basket in a patient with bilateral hippocampus infarct.
Radiol Case Rep
February 2025
Department of Pathology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Sawangi (Meghe), Wardha, Maharashtra, India, 442001.
The occurrence of isolated bilateral hippocampus infarct is extremely rare and is thought to be associated with a number of etiologies, including ischemia, infection, paraneoplastic syndromes, seizures, drug addiction, etc. The presented manuscript depicts a case of a 28-year-old male patient who has been a chronic alcoholic for the past 4 years and, on imaging, was found to have a bilateral hippocampal infarct in isolation. Also, the manuscript presents the appearance of the magnetic resonance imaging (MRI) of Bochdalek's flower basket, which is an anatomical variant of the choroid plexus in the fourth ventricle.
View Article and Find Full Text PDFBOLD-CSF dynamics assessed using real-time phase contrast CSF flow interleaved with cortical BOLD MRI.
Fluids Barriers CNS
December 2024
C.J. Gorter MRI Center, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands.
Background: Cerebrospinal fluid (CSF) motion and pulsatility has been proposed to play a crucial role in clearing brain waste. Although its driving forces remain debated, increasing evidence suggests that large amplitude vasomotion drives such CSF fluctuations. Recently, a fast blood-oxygen-level-dependent (BOLD) fMRI sequence was used to measure the coupling between CSF fluctuations and low-frequency hemodynamic oscillations in the human cortex.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!