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Article Abstract
Objective: To explore the correlation between changes in esophageal pressure and psychological status in patients with globus sensation.
Methods: A total of 40 patients with globus sensation who attended Wenzhou People's Hospital between August 2020 and February 2021 were divided into two groups based on the results of esophageal manometry: a high-pressure group and a non-high-pressure group. The duration of disease, clinical symptom score, and self-rating anxiety scale (SAS) were compared between the two groups to determine the relationship between changes in esophageal pressure and psychological status.
Results: All the patients before treatment were divided into a high-pressure group (n = 14) and a non-high-pressure group (n = 26) according to whether the resting pressure of the upper esophageal sphincter (UES) was greater than 104 mmHg. The differences between the high-pressure group and non-high-pressure group in duration of disease, clinical symptom score, and SAS were statistically significant (all < 0.05). Anxiety was present in 12 patients in the high-pressure group and two patients in the non-high-pressure group. The difference between the the high-pressure group and non-high-pressure group in the incidence of anxiety was statistically significant (χ = 21.04 and < 0.001). Pearson correlation analysis of the association between esophageal pressure and anxiety resulted in R = 0.74 and < 0.001.
Conclusion: Patients with globus sensation who develop anxiety were more likely to have high pressure in the upper esophageal sphincter.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630375 | PMC |
| http://dx.doi.org/10.2147/IJGM.S337165 | DOI Listing |
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