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http://dx.doi.org/10.1128/JCM.02262-21 | DOI Listing |
Vaccine
February 2024
Dhirubhai Ambani Life Sciences Centre, Reliance Life Sciences Pvt. Ltd., Rabale, Navi Mumbai 400701, India. Electronic address:
SARS-CoV-2, severe acute respiratory syndrome coronavirus-2, causes coronavirus disease- 2019 (COVID-19). Mostly, COVID-19 causes respiratory symptoms that can resemble those of a cold, the flu, or pneumonia. COVID-19 may harm more than just lungs and respiratory systems.
View Article and Find Full Text PDFAnaesthesiologie
November 2023
Institut für Infektionsmedizin und Krankenhaushygiene, Universitätsklinikum Jena, Jena, Deutschland.
Background: In the German hospital landscape and emergency care the COVID-19 pandemic was a stress test. Emergency medical health care in Germany is ensured by the supply chain between prehospital emergency rescue and clinical emergency care in the emergency rooms. In hospitals and emergency care settings a rapid, simple, accurate, and cost-effective test is needed to identify SARS-CoV‑2.
View Article and Find Full Text PDFVaccines (Basel)
September 2023
Division of Infectious Diseases, City of Hope National Medical Center, Duarte, CA 91010, USA.
Hematopoietic cell transplantation (HCT) and chimeric antigen receptor (CAR)-T cell patients are immunocompromised, remain at high risk following SARS-CoV-2 infection, and are less likely than immunocompetent individuals to respond to vaccination. As part of the safety lead-in portion of a phase 2 clinical trial in patients post HCT/CAR-T for hematological malignancies (HM), we tested the immunogenicity of the synthetic modified vaccinia Ankara-based COVID-19 vaccine COH04S1 co-expressing spike (S) and nucleocapsid (N) antigens. Thirteen patients were vaccinated 3-12 months post HCT/CAR-T with two to four doses of COH04S1.
View Article and Find Full Text PDFBiosens Bioelectron
November 2023
São Carlos Institute of Chemistry, University of São Paulo, São Carlos, SP, 13560-970, Brazil. Electronic address:
The emergence of the graphene-based hybrid electrical-electrochemical vertical device (EEVD) has introduced a promising nanostructured biosensor tailored for point-of-care applications. In this study, we present an innovative EEVD capable of simultaneously detecting the receptor binding domain (RBD) of the SARS-CoV-2 spike protein in both serum and saliva. The foundation of the EEVD lies in a poly-neutral red-graphene heterojunction, which has been enhanced with a bioconjugate of gold nanoparticles and antibodies.
View Article and Find Full Text PDFOpen Life Sci
August 2023
Facultad de Farmacia, Instituto de Investigaciones Farmacéuticas (INIFAR), Universidad de Costa Rica, San José, Costa Rica.
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