Infants Younger Than 6 Months Infected With SARS-CoV-2 Show the Highest Respiratory Viral Loads.

J Infect Dis

Universidad de Buenos Aires-Instituto de Investigaciones Biomédicas en Retrovirus y SIDA, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina.

Published: February 2022

AI Article Synopsis

  • - Researchers studied over 45,000 SARS-CoV-2 positive samples in Buenos Aires, focusing on infants, as previous studies often combined infants with older children.
  • - Infants under 6 months had higher viral loads compared to all other age groups, while children older than 6 months had viral loads similar to adults.
  • - These findings suggest that infants may play a different role in the spread of SARS-CoV-2, prompting further research into their infection characteristics.

Article Abstract

There is a paucity of reports on the characteristics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in infants, because most studies have grouped infants with older children. We analyzed the viral loads of 45318 SARS-CoV-2-positive nasopharyngeal swab samples obtained in Buenos Aires, Argentina. Infants younger than 6 months presented higher viral loads than any other age group. Children older than 6 months showed significantly lower viral loads, similar to those founds in adults. This observation raises new questions regarding the role of infants in the spreading of SARS-CoV-2 infection.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8690165PMC
http://dx.doi.org/10.1093/infdis/jiab577DOI Listing

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