The diagnosis of Crohn's disease has been considered a contraindication to the construction of a Kock continent ileostomy. From 1975 to 1984, 95 Kock continent ileostomies were performed at the Stanford University Medical Center. The clinical course of seven patients with regional enteritis who were disease-free for five years was reviewed. All of the patients studied were women, with a mean disease-free interval of 7.7 years and a range of follow-up study of four to 50 months. To date, all of the patients are fully continent to gas and ileal effluent. The postoperative complication and revision rate (28 per cent) was comparable with the results cited in the literature for individuals with ulcerative colitis or familial polyposis. When revisions were necessary, patients elected to keep the Kock pouch rather than conversion to a conventional Brooke ileostomy. The authors agree that active regional enteritis is to be considered a contraindication to the construction of a continent ileostomy. However, the benefits afforded a patient with a continent ileal reservoir are substantial and warrant consideration in a select group of patients with Crohn's disease who are disease-free for a minimum of five years.
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Tech Coloproctol
October 2024
Ellen Leifer Shulman and Steven Shulman Digestive Disease Center, Cleveland Clinic Florida, 2950 Cleveland Clinic Blvd, Weston, FL, 33331, USA.
Dis Colon Rectum
June 2024
Division of Colorectal Surgery, Center for Inflammatory Bowel Disease, Columbia University Irving Medical Center-New York Presbyterian Hospital, New York, New York.
Background: The IPAA has been successful in restoring intestinal continuity and preserving continence in the majority of patients requiring a proctocolectomy. However, a subset of individuals experience significant complications that might result in pouch failure. The conversion of the J-pouch to a continent ileostomy pouch represents a significant surgical procedure.
View Article and Find Full Text PDFAnimals (Basel)
July 2023
Biophysics Department, GSI Helmholtzzentrum für Schwerionenforschung, 64291 Darmstadt, Germany.
Following population declines of the African savanna elephant () across the African continent, the establishment of primary cell lines of endangered wildlife species is paramount for the preservation of their genetic resources. In addition, it allows molecular and functional studies on the cancer suppression mechanisms of elephants, which have previously been linked to a redundancy of tumor suppressor gene . This methodology describes the establishment of primary elephant dermal fibroblast (EDF) cell lines from skin punch biopsy samples (diameter: ±4 mm) of African savanna elephants ( = 4, 14-35 years).
View Article and Find Full Text PDFDis Colon Rectum
November 2023
Department of Surgery, Linköping University Hospital, Linköping, Sweden.
Background: Kock's continent ileostomy is an option after proctocolectomy for patients not suitable for IPAA or ileorectal anastomosis. Ulcerative colitis is the most common indication for continent ileostomy.
Objective: The aim of this study was to evaluate the long-term outcome of continent ileostomy.
Clin Colon Rectal Surg
November 2022
Department of Surgery, Atrium Health Wake Forest Baptist Medical Center, Winston-Salem, North Carolina.
The continent ileostomy (CI) was popularized by Nils Kock as a means to provide fecal continence to patients, most commonly in those with ulcerative colitis, after proctocolectomy. Although the ileal pouch-anal anastomosis (IPAA) now represents the most common method to restore continence after total proctocolectomy, CI remains a suitable option for highly selected patients who are not candidates for IPAA or have uncorrectable IPAA dysfunction but still desire fecal continence. The CI has exhibited a fascinating and marked evolution over the past several decades, from the advent of the nipple-valve to a distinct pouch design, giving the so-inclined and so-trained colorectal surgeon a technique that provides the unique patient with another option to restore continence.
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