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In the context of bulk grain container transportation, the complex logistics can lead to grain mildew and subsequent economic losses. Therefore, there is a pressing need to explore swift and real-time mildew detection technology. Our investigation, simulating actual transportation conditions, revealed that , , and were the primary molds responsible for soybean mildew during container transportation.
View Article and Find Full Text PDFUnsaturated fatty acid perturbation combats emerging triazole antifungal resistance in the human fungal pathogen .
mBio
July 2024
Microbiology and Immunology Department, Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire, USA.
Contemporary antifungal therapies utilized to treat filamentous fungal infections are inhibited by intrinsic and emerging drug resistance. Consequently, there is an urgent need to develop novel antifungal compounds that are effective against drug-resistant filamentous fungi. Here, we utilized an cell-based high-throughput screen to identify small molecules with antifungal activity that also potentiated triazole activity.
View Article and Find Full Text PDFCharacterizing the Contribution of Functional Microbiota Cultures in Pit Mud to the Metabolite Profiles of Fermented Grains.
Foods
May 2024
College of Biomass Science and Engineering, Sichuan University, Chengdu 610065, China.
Elevating the flavor profile of strong flavors has always been a focal point in the industry, and pit mud (PM) serves as a crucial flavor contributor in the fermentation process of the fermented grains (FG). This study investigated the influence of wheat flour and bran (MC and FC) as PM culture enrichment media on the microbiota and metabolites of FG, aiming to inform strategies for improving strong-flavor flavor. Results showed that adding PM cultures to FG significantly altered its properties: FC enhanced starch degradation to 51.
View Article and Find Full Text PDFMore than meets the eye: rhino-orbital cerebral mucormycosis with diabetic ketoacidosis presenting as periorbital edema resulting in orbital exenteration and maxillectomy.
Proc (Bayl Univ Med Cent)
February 2024
Baylor Scott and White Heart and Vascular Hospital - Fort Worth, Baylor Scott and White All Saints Medical Center, Fort Worth, Texas, USA.
Mucormycosis is an invasive fungal infection that can cause acute clinical decompensation and death. The literature demonstrates case fatality rates around 50% with differential clinical courses contingent upon anatomical incursion. Rhino-orbital cerebral mucormycosis represents a rapidly hostile variant with poorer outcomes, warranting prompt recognition, workup, and intervention.
View Article and Find Full Text PDFIn Vitro and In Vivo Assessments of Anti-Hyperglycemic Properties of Soybean Residue Fermented with and .
Life (Basel)
October 2022
Department of Microbiology, Immunology and Biopharmaceuticals, National Chiayi University, Chiayi 600355, Taiwan.
Soy isoflavones possess antioxidative, anti-inflammatory, anti-diabetic and phytoestrogenic properties. Soybean residue contains a fair amount of nutrients such as glycosylated isoflavones, minerals and dietary fibers, and is a substantial waste product produced from soymilk and tofu manufacturing. A solid-state fermentation of soybean residue by or co-inoculated with improves the availability of isoflavones and GABA content which is attributed to ameliorated hyperglycemic symptoms in STZ-induced hyperglycemic mice.
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