Residual antibiotics in food products originated from administration of the antibiotics to animals may be accumulated through food metabolism in the human body and endanger safety and health. Thus, developing a prompt and accurate way for detection of antibiotics is a crucial issue. The zero-dimensional fluorescent probes including metals based, carbon and graphene quantum dots (QDs), are highly sensitive materials to use for the detection of a wide range of antibiotics in natural products. These QDs demonstrate unique optical properties like tunable photoluminescence (PL) and excitation-wavelength dependent emission. This study investigates the trends related to carbon and metal based QDs preparation and modification, and their diverse detection application. We discuss the performance of QDs based sensors application in various detection systems such as photoluminescence, photoelectrochemical, chemiluminescence, electrochemiluminescence, colorimetric, as well as describing their working principles in several samples. The detecting mechanism of a QDs-based sensor is dependent on its properties and specific interactions with particular antibiotics. This review also tries to describe environmental application and future perspective of QDs for antibiotics detection.
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