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Surgical valve replacement in adults late after total cavo-pulmonary connection/Fontan procedure.
Eur J Cardiothorac Surg
November 2024
Adult Congenital Heart Diseases Unit, Royal Brompton and Harefield Hospitals, Part of Guy's and St Thomas's NHS Foundation Trust, London, UK.
Objectives: There is dearth of data on long-term outcomes of systemic semilunar (SS) or atrioventricular (AV) valve operation in adult patients with a Fontan circulation. We describe a single-centre experience of adults who underwent valve surgery late after a Fontan procedure.
Methods: We retrospectively reviewed all patients with a Fontan circulation who had a reoperation for severe valve disease during adulthood in our centre.
Rescue Transcatheter Native Aortic Valve Closure to Treat Severe Aortic Regurgitation in a Patient With Single Ventricular Physiology and Decompensated Heart Failure.
Catheter Cardiovasc Interv
December 2024
Department of Paediatric Cardiology, Leeds Teaching Hospitals Trust, Leeds, UK.
Semilunar valve regurgitation in single ventricular physiology is rare but portends a poor prognosis. Medical therapy is often ineffective particularly in the context of structural valve abnormality, and surgical valve repair or replacement can be associated with poor outcomes. We report an innovative use of a highly occlusive and conformable Gore Septal Occluder for transcatheter treatment of severe native aortic regurgitation in a symptomatic patient with hypoplastic left heart syndrome and severe systemic right ventricular dysfunction, resulting in safe and complete occlusion of the aortic regurgitant orifice and clinical benefit.
View Article and Find Full Text PDFMolecular Pathways and Animal Models of Semilunar Valve and Aortic Arch Anomalies.
Adv Exp Med Biol
June 2024
Newcastle University Biosciences Institute, Newcastle upon Tyne, UK.
The great arteries of the vertebrate carry blood from the heart to the systemic circulation and are derived from the pharyngeal arch arteries. In higher vertebrates, the pharyngeal arch arteries are a symmetrical series of blood vessels that rapidly remodel during development to become the asymmetric aortic arch arteries carrying oxygenated blood from the left ventricle via the outflow tract. At the base of the aorta, as well as the pulmonary trunk, are the semilunar valves.
View Article and Find Full Text PDFSystolic Time Interval Extraction in Hypertensive and Hypotensive Pig Models Using Wearable Near-Field Radio-Frequency Sensors.
Annu Int Conf IEEE Eng Med Biol Soc
July 2023
Screening and monitoring for cardiovascular diseases (CVDs) can be enabled by analyzing systolic time intervals (STIs). As CVDs have a strong causal correlation with hypertension, it is important to validate STI sensor accuracy in hypertensive hearts to ensure consistent performance in this prevalent cardiac disease state. This work presents STI extraction using a non-invasive near-field radio-frequency (RF) sensor during normotension, hypertension, and hypotension in a pig model.
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