Background: Tannins are considered an important phytochemical used in cosmetics and cosmeceuticals and are well-known for their astringent and antioxidant properties. is a plant that grows in the Southern part of Thailand. Its fruits have an astringent taste, which might correlate with the presence of tannins.
Objective: We sought to evaluate the efficacy of a hydrogel containing extract for controlling sebum.
Methods: First, the extract of fruit was evaluated for its tannin content and astringent activity . Then it was formulated into a hydrogel in different concentrations. After, the safety and sebum-control efficacy of this hydrogel was tested in 10 healthy volunteers. The safety of this hydrogel was evaluated in volunteers using a closed patch test.
Results: The results of the first part of the study indicated that extract contained 0.0359±0.0003mg of tannic acid equivalent per gram of extract, and its astringent activity was 87.45%±1.76%. When formulated into hydrogels of different concentrations, the results showed that the hydrogel containing 0.1% w/w had the highest stability profile. No irritation or allergy was observed. Separately, after usage twice per day for 28 consecutive days, the sebum content of the volunteers was decreased by -54.36%±13.71% relative to baseline.
Conclusion: The results from this study suggest that fruit extract might be an effective active ingredient for use by the cosmetic and cosmeceutical industry.
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