AI Article Synopsis
- - Antineutrophil cytoplasmic antibody-associated vasculitis (AAV) is a systemic condition that leads to inflammation of blood vessels in various organs, with infection potentially triggering its onset.
- - Research indicates that a cytokine storm from the immune response to SARS-CoV-2 can worsen AAV symptoms in infected individuals.
- - The study emphasizes the importance of vaccination and preventive education for patients on immunosuppressive therapy, even post-COVID-19 infection, as it impacts antibody levels and overall health management.
Article Abstract
Antineutrophil cytoplasmic antibody-associated vasculitis (AAV) is a systemic disease that causes vasculitis in various organs. Although the cause of the onset is unknown, infection has been reported to be a causative factor. The subsequent cytokine storm triggered by the immune response against SARS-CoV-2 infection has been reported to lead to symptoms being more severe. We herein report our experience with the onset of AAV following COVID-19 infection. We also report the course of anti-SARS-CoV-2 serum antibody titers following induction therapy, which suggests that vaccination and education concerning standard precautions are necessary in patients who require immunosuppressive therapy, even after COVID-19 infection.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907777 | PMC |
| http://dx.doi.org/10.2169/internalmedicine.8615-21 | DOI Listing |
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