Isolation and characterization of N-phenyl propoxyphenyl carbodenafil from an illegal coffee powder product.

A new carbodenafil-like compound, N-phenyl propoxyphenyl carbodenafil has been identified from an illegal coffee powder product. It was isolated using a semi-preparative liquid chromatography column. The presence of a propoxy group at the aryl alkyl ether moiety, and the direct bonding of a phenyl group to piperazine ring have been unambiguously characterized by ultra-violet (UV), Fourier transform infrared (FTIR), high-resolution mass spectrometry (HRMS) and nuclear magnet resonance (NMR) analysis.