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High-grade trichoblastic carcinoma with sarcomatoid differentiation harboring TP53 and PIK3CA mutations.
Ann Dermatol Venereol
March 2022
Department of pathology, université de Tours, CHU de Tours, avenue de la République, 37170 Chambray-lès-Tours, France; "Biologie des Infections à Polyomavirus" Team, UMR Inrae ISP 1282, université de Tours, 31, avenue Monge, 37200 Tours, France.
Morphologically high-grade trichoblastic carcinoma: a clinicopathological study with long-term clinical follow-up.
Histopathology
June 2021
Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Aims: Trichoblastic carcinomas (malignant trichoblastomas) are rare and poorly documented neoplasms characterised by malignant transformation of a pre-existing benign trichoblastoma, and are subdivided histologically into low-grade and high-grade tumours. Whereas morphologically low-grade trichoblastic carcinomas show indolent behaviour, morphologically high-grade trichoblastic carcinomas have been associated with a poor prognosis, but little is known about their true biological potential. The aim of this study was to better define the clinicopathological features and outcomes of morphologically high-grade trichoblastic carcinomas.
View Article and Find Full Text PDFPinna high grade trichoblastic carcinoma, a report.
Clin Pract
September 2020
Head, Plastic and Reconstructive Surgery, Lebanese Hospital Geitaoui-UMC, Beirut, Lebanon.
Trichoblastic carcinoma is a rare malignant hair follicle tumor. It resembles basal cell carcinoma clinically, but different studies emphasize on the importance of differentiating between these two cancers since they have different clinical course which may affect treatment options and follow up. Regardless of its aggressive behavior, no consensus is present for the treatment of trichoblastic carcinoma.
View Article and Find Full Text PDF18F-FDG PET/CT Imaging of Trichoblastic Carcinoma With Nodal Metastasis.
Clin Nucl Med
July 2019
Laboratory Medicine and Pathology, Mayo Clinic, Scottsdale, AZ.
Trichoblastic carcinoma is an uncommon malignant neoplasm arising from follicular germinative cells. The high-grade trichoblastic carcinoma has been reported with lymphatic and hematogenous dissemination. The authors present a 59-year-old man with gluteal cleft trichoblastic carcinoma and highlight the useful role of serial F-FDG PET/CT examinations in the demonstration of initial and subsequent nodal metastasis in the inguina and pelvis.
View Article and Find Full Text PDFA trichogenic tumor with aggressive features initially diagnosed as basal cell carcinoma.
Dermatol Online J
September 2018
Department of Dermatology, University School of Medicine, Durham, North Carolina.
Trichoblastic carcinoma is a rare carcinoma often arising in a pre-existing trichoblastoma. It may resemble basal cell carcinoma, posing a diagnostic challenge. Trichoblastic carcinoma is divided into low-grade and high-grade tumors.
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