AI Article Synopsis
- * Epigenetic alterations are increasingly recognized as significant in cancer progression, leading to the exploration of targeted drugs that affect various epigenetic pathways.
- * The review focuses on examining the anticancer properties of natural compounds, particularly alkaloids, terpenoids, quinones, and isothiocyanates derived from medicinal plants.
Article Abstract
Cancer is one of the most complex and systemic diseases affecting the health of mankind, causing major deaths with a significant increase. This pathology is caused by several risk factors, of which genetic disturbances constitute the major elements, which not only initiate tumor transformation but also epigenetic disturbances which are linked to it and which can induce transcriptional instability. Indeed, the involvement of epigenetic disturbances in cancer has been the subject of correlations today, in addition to the use of drugs that operate specifically on different epigenetic pathways. Natural molecules, especially those isolated from medicinal plants, have shown anticancer effects linked to mechanisms of action. The objective of this review is to explore the anticancer effects of alkaloids, terpenoids, quinones, and isothiocyanates.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621755 | PMC |
| http://dx.doi.org/10.3390/nu13113714 | DOI Listing |
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