The Fellowship of Privileged Scaffolds-One Structure to Inhibit Them All.

Pharmaceuticals (Basel)

Department of Organic and Medicinal Chemistry, Faculty of Chemistry, Wroclaw University of Science and Technology, Wybrzeze Wyspianskiego 27, 50-370 Wrocław, Poland.

Published: November 2021

Over the past few years, the application of privileged structure has emerged as a powerful approach to the discovery of new biologically active molecules. Privileged structures are molecular scaffolds with binding properties to the range of different biological targets. Moreover, privileged structures typically exhibit good drug-like properties, thus assuring more drug-like properties of modified compound. Our main objective is to discuss the privileged structures used for the development of antiviral agents.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622370PMC
http://dx.doi.org/10.3390/ph14111164DOI Listing

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