as a Good Model to Study Pathogenesis.

The invertebrate model, , has been widely used to study host-pathogen interactions due to its cheapness, ease of handling, and similar mammalian innate immune system. larvae have been proven to be useful and a reliable model for analyzing pathogenesis mechanisms of multidrug resistant an opportunistic pathogen difficult to kill. This review describes the detailed experimental design of / models, and provides a comprehensive comparison of various virulence factors and therapy strategies using the host. These investigations highlight the importance of this host-pathogen model for in vivo pathogen virulence studies. On the long term, further development of the / model will offer promising insights for clinical treatments of infection.