These data are related to our previous paper "Synthesis and approbation of new neuroprotective chemicals of pyrrolyl- and indolylazine classes in a cell model of Alzheimer's disease" (Dutysheva et al., 2021), in which we demonstrate neuroprotective abilities of pyrrolyl- and indolylazines in a cell model of Alzheimer's disease. Using a novel procedure of photocatalysis we have synthesized a group of new compounds. The current article presents nuclear magnetic resonance spectra including heteronuclear single quantum coherence spectra of chemicals synthesized by us. The effect of new compounds have on heat shock proteins genes expression in reprogrammed human neurons are presented. We also presented data that verify neuronal phenotype of reprogrammed cells.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605230PMC
http://dx.doi.org/10.1016/j.dib.2021.107562DOI Listing

Publication Analysis

Top Keywords

pyrrolyl- indolylazines
8
heat shock
8
genes expression
8
human neurons
8
cell model
8
model alzheimer's
8
dataset nmr-spectra
4
nmr-spectra pyrrolyl-
4
indolylazines evidence
4
evidence ability
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!