AI Article Synopsis
- * A case study of a 38-year-old woman illustrates how digital dermoscopic monitoring detected changes in her moles, leading to the discovery of dysplastic nevi, which were later surgically removed.
- * There is a significant connection between dysplastic nevus syndrome and pancreatic cancer, highlighting the need for regular skin check-ups and cancer screenings in patients at risk, particularly those with familial atypical multiple mole melanoma syndrome (FAMMM).
Article Abstract
Multiple primary cancers may occur in the same patient, with a prevalence that follows an ascendant trend. Their development is dictated by a complex interplay between a variety of factors, both patient-dependent and external. The case of a 38-year-old female patient diagnosed and treated for pancreatic cancer (PC) is presented in whom the digital dermoscopic monitoring of melanocytic nevi revealed a marked change of two nevi that acquired rapidly highly atypical features. They were surgically excised and the histopathological examination revealed two completely excised dysplastic compound nevi. Clinicians should be aware of the strong association between dysplastic nevus syndrome and PC, a malignancy associated with an extremely poor prognosis. Familial atypical multiple mole melanoma syndrome (FAMMM) predisposes to the development of melanoma, pancreatic cancer and other neoplasms. The common genetic background of PC and hereditary melanoma is discussed and the importance of regular skin checkup and screening for PC in these patients is underlined.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8611490 | PMC |
| http://dx.doi.org/10.3892/etm.2021.10953 | DOI Listing |
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