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Influence of Low-Level Laser Irradiation of the Red and Infrared Spectral Range for Treating Chronic Testicular Pain: A Randomized Clinical Trial.
J Lasers Med Sci
December 2024
Laser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
The treatment of chronic testicular pain is a complex condition that will be encountered by most practicing clinicians. In this study, the influence of low-level laser irradiation of the red and infrared spectral range for treating chronic testicular pain was evaluated and compared. In this double-blind, placebo-controlled randomized clinical trial study, 60 patients were randomly divided into three groups of 20: (1) low-level laser group with red (650 nm, 50 mW), (2) low-level laser group with infrared (820 nm, 100 mW) and (3) laser placebo group.
View Article and Find Full Text PDFRemote photobiomodulation ameliorates behavioral and neuropathological outcomes in a rat model of repeated closed head injury.
Transl Psychiatry
January 2025
Laboratory of Exercise and Neurobiology, School of Physical Education and Sports Science, South China Normal University, Guangzhou, 510006, Guangdong, China.
Repeated closed-head injuries (rCHI) from activities like contact sports, falls, military combat, and traffic accidents pose a serious risk due to their cumulative impact on the brain. Often, rCHI is not diagnosed until symptoms of irreversible brain damage appear, highlighting the need for preventive measures. This study assessed the prophylactic efficacy of remote photobiomodulation (PBM) targeted at the lungs against rCHI-induced brain injury and associated behavioral deficits.
View Article and Find Full Text PDFMolecular evidence for the efficacy of PBM therapy in the treatment of Oral lichen planus.
Photodiagnosis Photodyn Ther
January 2025
Department of Healthcare and Social Work, New Bulgarian University, Sofia, Bulgaria. Electronic address:
Purpose: Oral lichen planus (OLP) is a chronic inflammatory disease, in which T-Lymphocytes induce apoptosis of basal keratinocytes, leading to the formation of symptomatic lesions. It is assumed that blocking the cell death program and enhancing cell proliferation would be crucial to the healing process. The aim of the study was to verify the efficacy of Photobiomodulation (PBM) in OLP management, by evaluating the effects of laser irradiation on the processes of apoptosis and cell proliferation.
View Article and Find Full Text PDFEfficacy of Repeated Low-Level Red Light (RLRL) Therapy in Managing Childhood Myopia: A Systematic Review and Meta-Analysis.
J Clin Med
December 2024
Faculty of Physics, University of Warsaw, Pasteura 5, 02-093 Warszawa, Poland.
: As Repeated Low-Level Red Light (RLRL) therapy is becoming increasingly prevalent in clinical practice, mainly in the Far East, largely due to its child-friendly nature and the feasibility of home use, this study aims to conduct a systematic review and meta-analysis to evaluate the efficacy of RLRL therapy in managing childhood myopia, specifically in relation to axial length (AL) and spherical equivalent refraction (SER), across a larger group of children aged from 6 to 16 years. : A systematic literature search was performed using PubMed, Scopus, and Web of Science to access relevant databases and to locate outcome studies. Eligibility criteria included publication type, participant characteristics, and outcomes report.
View Article and Find Full Text PDFOptimizing Photobiomodulation Radiometric and Spectral Parameters In Vitro to Enhance Angiogenesis and Mitochondrial Function.
Int J Mol Sci
December 2024
Laboratory for Functional and Metabolic Imaging (LIFMET), Institute of Physics, Swiss Federal Institute of Technology (EPFL), Station 3, 1015 Lausanne, Switzerland.
Photobiomodulation (PBM) therapy, a therapeutic approach utilizing low-level light, has garnered significant attention for its potential to modulate various biological processes. This study aimed at optimizing and investigating the effects of PBM on angiogenesis and mitochondrial metabolic activity. In vitro experiments using human umbilical vein endothelial cells (HUVECs) and vascular smooth muscle cells (VSMCs) were performed to assess PBM's impacts on cell migration, proliferation, endogenous protoporphyrin IX production, mitochondrial membrane potential, Rhodamine 123 fluorescence lifetime, mitochondrial morphology, and oxygen consumption.
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