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The distribution and evolutionary dynamics of dopaminergic neurons in molluscs.
bioRxiv
June 2024
Whitney Laboratory, University of Florida, St. Augustine, FL, USA.
Dopamine is one of the most versatile neurotransmitters in invertebrates. It's distribution and plethora of functions is likely coupled to feeding ecology, especially in Euthyneura (the largest clade of molluscs), which presents the broadest spectrum of environmental adaptations. Still, the analyses of dopamine-mediated signaling were dominated by studies of grazers.
View Article and Find Full Text PDFEthyl Acetate Fraction of Harpagophytum procumbens Prevents Oxidative Stress In Vitro and Amphetamine-Induced Alterations in Mice Behavior.
Neurochem Res
June 2023
Departamento de Morfologia, Universidade Federal de Santa Maria, Santa Maria, Rio Grande do Sul, Brazil.
Microglial activation has been associated to the physiopathology of neurodegenerative diseases, such as schizophrenia, and can occur during inflammation and oxidative stress. Pharmacological treatment is associated with severe side effects, and studies for use of plant extracts may offer alternatives with lower toxicity. Harpagophytum procumbens (HP) is a plant known for its anti-inflammatory properties.
View Article and Find Full Text PDFThe devil is in the task structure.
Elife
April 2022
Department of Cognitive Sciences, University of Haifa, Haifa, Israel.
Conflicting evidence about how the brain processes social and individual learning stems from which type of information is presented as the primary source of knowledge during experiments.
View Article and Find Full Text PDFDopamine devils.
Arq Neuropsiquiatr
November 2021
University College London, Institute of Neurology, Department of Clinical Movement Disorder and Neuroscience, Reta Lila Weston Institute of Neurological Studies, London, UK.
What a relief! A role for dopamine in positive (but not negative) valence.
Neuropsychopharmacology
July 2018
National Institute on Drug Abuse, Baltimore, MD, 21224, USA.
We have long known that dopamine encodes the predictive relationship between cues and rewards. But what about relief learning? In this issue of Neuropsychopharmacology, Mayer et al. show that the same circuits encoding rewarding events also encode relief from aversive events.
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